Results 61 to 70 of about 3,066,070 (344)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Protection of DC microgrids

, 2023
Tema ovoga rada bila je zaštita istosmjernih mikromreža. Kako bi se čitatelj pobliže upoznao sa pojmom istosmjernih mikromreža na početku rada definirane su osnovne komponente.
Erik, Deni
core   +2 more sources

Response of carrot seed germination to heat treatment, the emergency measure to reduce the risk of ‘Candidatus Liberibacter solanacearum’ seed transmission

Phytopathologia Mediterranea, 2023
In Europe and the Mediterranean region, ‘Candidatus Liberibacter solanacearum’ (Lso) is associated with emerging diseases of Apiaceae crops, mainly carrot.
Lorenza TIZZANI, Andrea GENTILI, Anna TAGLIENTI, Sabrina BERTIN, Vincenza ILARDI   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

A comprehensive review of hybrid AC/DC networks: insights into system planning, energy management, control, and protection

Neural computing & applications (Print)
The introduction of hybrid alternating current (AC)/direct current (DC) distribution networks led to several developments in smart grid and decentralized power system technology. The paper concentrates on several topics related to the operation of hybrid
Mohamed I. Abdelwanis, Mohammed I. Elmezain   +1 more
semanticscholar   +1 more source

Susceptibility of olive fruit fly, Bactrocera oleae (Diptera: Tephritidae) pupae to entomopathogenic nematodes

Journal of Plant Protection Research, 2017
The olive fruit fly Bactrocera oleae is one of the most serious and economically damaging insects worldwide, affecting the quality and quantity of both olive oil and table olives.
Torrini Giulia, Mazza Giuseppe, Benvenuti Claudia, Roversi Pio Federico   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Novel short‐circuit protection technique for DC–DC buck converters

IET Circuits, Devices & Systems, 2014
This study presents a novel short‐circuit protection technique for DC–DC buck converters. The required short‐circuit operating frequency is derived in order to avoid the effect of inherent propagation delay in the controller and power transistors.
Yajun Li, Xinquan Lai, Qiang Ye, Bing Yuan   +3 more
openaire   +1 more source

Enhanced Fault Detection and Localization Strategy for High-Speed Protection in Medium-Voltage DC Distribution Networks Using Extended Kalman Filtering Algorithm

IEEE Access
Conventional strategies are not effective in addressing the complex protection challenges in medium-voltage DC distribution networks (MVDCDN). The main challenge in MVDCDN is the high-rising DC fault current, requiring a robust and fast protection ...
Nauman Ali Larik, M. Li, Qing-Hua Wu
semanticscholar   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source