Results 31 to 40 of about 6,327 (313)

Calculation and control of DC bias current distribution in an AC power system around a typical ±800 kV DC grounding electrode

open access: yesThe Journal of Engineering, 2019
When the ultra-high-voltage direct current (UHVDC) transmission system operates in a monopolar ground return mode, an enormous DC current flows into earth via the DC grounding electrode in the converter station and then comes into the AC system around ...
Fangjie Wu   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Planar transformer isolated DC-DC Converter for Solid-State Transformer

open access: yes, 2020
The demand for high frequency, high power density and high efficiency on power converters has been increasing through the years. Solid state transformer (SST), which is typically formed by three stages, one being DC/AC inverter, which is controllable, one being medium-frequency transformer isolated converter and the other being AC/DC rectifier, has ...
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Design of high voltage and large capacity DC transformers based on capacitive power transfer principle

open access: yesZhejiang dianli
DC transformers serve as critical infrastructure for interconnecting DC systems at different voltage levels and constructing DC power grids. The development of cost-effective, high-efficiency, and lightweight DC transformers remains a pivotal research ...
XI Guangyu, XU Jianjun, ZHU Jingpeng
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Reduction of geomagnetically induced current impacts by optimized neutral point connections

open access: yesIET Generation, Transmission & Distribution, 2023
Solar storms impact electrical power grids by causing quasi‐DC neutral point currents in transformers. These currents lead to half‐cycle saturation as well as other related and unwanted effects in the grid.
Philipp Schachinger   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Research on Current Limiting Method Used for Short Circuit Fault Current of Resonant DC Transformer Based on Inverted Displacement Phase Control

open access: yesIEEE Access, 2020
Due to the characteristics of high efficiency and flexible transformation ratio, full-bridge CLLC resonant DC transformers have been increasingly used for DC grid in recent years.
Chaoran Zhuo   +3 more
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

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