Results 161 to 170 of about 2,262 (257)

Underexplored Catalysts as General Structures: Application of Machine Learning Techniques for Reaction‐Specific Datasets

open access: yesAngewandte Chemie, EarlyView.
Bias‐aware machine learning identified an underexplored imidazolidinone catalyst with broad competitive performance in iminium‐based reactions. Experimental benchmarking shows how data‐driven prioritization can uncover overlooked catalyst scaffolds from sparse and historically biased literature data.
Jiajing Li   +4 more
wiley   +1 more source

A High‐Voltage Membrane‐Free Li–Organic Hybrid Flow Battery Using Eutectic Lithium Chemistry

open access: yesAngewandte Chemie, EarlyView.
A high‐voltage (3.6 V) membrane‐free Li–organic hybrid flow battery is enabled by a deep‐eutectic lithium electrolyte composed of trifluoroacetamide (TFAD) and LiPF6, paired with a dichloromethane (DCM) catholyte containing phenothiazine (PTZ). The TFAD/LiPF6 eutectic provides fast Li+ transport and stable Li‐metal cycling, while the immiscible TFAD ...
Xiao Wang   +7 more
wiley   +1 more source

Chemically Regulated STING‐Activating Prodrugs of Deoxyribose Cyclic Dinucleotides Elicit Robust Immune Activation and Durable Antitumor Immunity

open access: yesAngewandte Chemie, EarlyView.
All three diastereoisomers of an esterase‐sensitive phosphotriester dCDN prodrug demonstrate improved activity. The (Rp,Rp) diastereoisomer shows the highest activity with an EC50 of 1.7 nM in STING activation and displays the most pronounced antitumor activity via intravenous administration, significantly suppressing tumor proliferation, extending the
Zhiqiang Xie   +14 more
wiley   +1 more source

DCMS analysis revealed differential selection signatures in the transboundary Sahiwal cattle for major economic traits. [PDF]

open access: yesSci Rep
Muansangi L   +11 more
europepmc   +1 more source

Azole γ‐Peptides Helix Switching via Heterocycle Substitutions

open access: yesAngewandte Chemie, EarlyView.
Heterocycle substitution in azole‐based γ‐amino acids enables control over the helical shape of heterocyclic γ‐peptides. S↔N permutation in thiazole residues switches a canonical 9‐helix into a flexible helix exhibiting discontinuous hydrogen bonding.
Samantha Chaise   +10 more
wiley   +1 more source

High-Temperature Stable Amorphous Al<sub>2-<i>x</i></sub>(ZrY)<sub><i>x</i></sub>O<sub>3</sub> Thin Film Insulators: An Alternative to Crystalline Alumina. [PDF]

open access: yesACS Appl Mater Interfaces
Salvadores Farran N   +11 more
europepmc   +1 more source

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