Results 111 to 120 of about 30,985 (226)

Real‐World Outcomes of Nivolumab and Ipilimumab in Metastatic Melanoma as Third Line and Beyond

International Journal of Cancer, Volume 159, Issue 7, Page 1780-1787, 1 October 2026.
Progression after anti‐PD‐1‐based therapy is a predominant scenario in metastatic melanoma. However, real‐world data informing treatment of metastatic melanoma in later lines remains scarce. This retrospective nationwide, population‐based cohort study shows in a real‐world setting that nivolumab plus ipilimumab can induce durable responses beyond the ...
Yago Garitaonaindia, Søren Kjær Petersen, Louise M. Guldbrandt, Troels H. Borch, Christina H. Ruhlmann, Rasmus Blechingberg Friis, Adam A. Luczak, Lars Bastholt, Henrik Schmidt, Inge Marie Svane, Eva Ellebaek, Marco Donia   +11 more
wiley   +1 more source

Coexisting adenomyosis in endometriosis: Similar pain and quality of life, with longer bleeding and bowel symptoms—A comparative cross‐sectional study

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 164-173, October 2026.
Abstract Objective To compare pain, menstrual flow, and quality of life (QoL) between women undergoing surgery for endometriosis only compared with women with endometriosis and coexisting adenomyosis. Methods A cross‐sectional study, set in two tertiary hospitals, of reproductive‐aged women (18–50 years) with a preoperative imaging diagnosis of ...
Mariana Matzenbacher Brunoro, Ana Clara Pimenta Servidoni, Sofia Di Nur Wakabayashi, Camila Rebeque Dagola, Marina Paula Andres, Mauricio Simoes Abrao   +5 more
wiley   +1 more source

Sono‐Anatomy and Histology of the Deep Fasciae in the Upper Limb

Journal of Ultrasound in Medicine, Volume 45, Issue 10, Page 2119-2140, October 2026.
The deep fascia of the upper limb represents a pivotal anatomical structure essential for effective force transmission, dynamic compartmentalization and musculoskeletal stability. Its composition (rich in type I collagen fibers) enables both mechanical resilience and functional adaptability, crucial for the upper limb's complex movements.
Carmelo Pirri, Nina Pirri, Lucia Petrelli, Veronica Macchi, Andrea Porzionato, Raffaele De Caro, Carla Stecco, Levent Özçakar   +7 more
wiley   +1 more source

A novel technique of rhinostomy size assessment by immersion b-scan probe following dacryocystorhinostomy - A comparative study. [PDF]

Indian J Ophthalmol
Mane S, Prabhakar SK, Malini MB, Sandeep S.   +3 more
europepmc   +1 more source

Provox Life HMEs for Pulmonary Rehabilitation in HME‐Naïve Laryngectomy Patients: A Randomized Controlled Trial

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 5, October 2026.
ABSTRACT Objective To evaluate whether Provox Life Heat and Moisture Exchangers (HMEs) and attachments enable HME‐naïve laryngectomized patients to establish a 24‐h HME routine, and whether the resulting effect on pulmonary symptoms is sustained over 9 months, compared with standard care. Methods In this prospective, randomized controlled trial, 79 HME‐
Rafael De Cicco, Rafael Pereira de Souza, Carla Gonçalves Soares Moreira, Sandra Lopez Calcines, Victor Bandini Vieira, Daniela Maria Santos Serrano Marquezin, Marianne Yumi Nakai, Marcelo Benedito Menezes, Tabata Briaunys Milan, Francisco Araújo Dias   +9 more
wiley   +1 more source

Predictive Value of On-Treatment Alpha-Fetoprotein Change for Lenvatinib Response in Patients with Hepatocellular Carcinoma: A Real-World Retrospective Study in Vietnam. [PDF]

Medicina (Kaunas)
Hoang NT, Le VQ, Tran T, Pham TQ, Nguyen TD, Hoang TC, Pham TP, Nguyen TH.   +7 more
europepmc   +1 more source

Timing of Effect Onset After Restarting Anti CGRP-(Receptor)-Monoclonal Antibodies Following a Mandatory Cessation After One year of Use–A Single Center Retrospective Cohort Study

Drug Design, Development and Therapy
Leonidas D Panos,1– 3,* Adrian Scutelnic,1,* Susan E Plüss,1 Jacqueline Bracher,1 Jean-Benoît Rossel,4 Mattia Branca,4 Franz Riederer,1 Christoph J Schankin1,5 1Department of Neurology, Inselspital, University Hospital Bern, University of
Panos LD, Scutelnic A, Plüss SE, Bracher J, Rossel JB, Branca M, Riederer F, Schankin CJ   +7 more
doaj  

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

DFRL-Mol: a dual-stage framework of reinforcement learning for multi-scenario molecule optimization. [PDF]

Brief Bioinform
Wu Z, Zhao P, Li J, Wang Q, Zhang Q, Yu H, Yu Z, Shi JY.   +7 more
europepmc   +1 more source

Ineffectiveness of immune checkpoint inhibitors in prostate cancer: is it just a question of ‘‐mabs’?

The Journal of Pathology, Volume 270, Issue 2, Page 139-162, October 2026.
Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi, Irene Torresan, Emilio Francesco Giunta, Sara Bleve, Nicole Brighi, Elisa Tassinari, Sofia Zanuccoli, Maria Concetta Cursano, Cristian Lolli   +8 more
wiley   +1 more source