Results 91 to 100 of about 30,985 (226)

ENDOSCOPIC DCR VERSUS EXTERNAL DCR

Journal of Evolution of Medical and Dental Sciences, 2015
Rukma Bhandary, Ajay A Kudva, Deepalakshmi Tanthry, Devan P P, Mahesh S G, Sowmya Sowmya, Sudhir Hegde K   +6 more
openaire   +1 more source

Italian Patients Journey for Gene Therapy in Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno, Gaia Spadarella, Alessandra Borchiellini, Anna Borrelli, Andrea Buzzi, Giancarlo Castaman, Michele Cecchi, Raimondo De Cristofaro, Vincenzo La Mura, Angelo Lupi, Giuseppe Malcangi, Maria Elisa Mancuso, Maria Francesca Mansueto, Cristina Santoro, Rita Carlotta Santoro, Luigi Piero Solimeno, Annarita Tagliaferri, Ezio Zanon, Isabella Garagiola, Flora Peyvandi   +19 more
wiley   +1 more source

Regional Community Building in Hard Times: Communal and Functional Filtering at EU Borders During the COVID‐19 Pandemic

JCMS: Journal of Common Market Studies, EarlyView.
Abstract Pandemics are times of closure. States typically restrict the entry of persons to protect their national communities from external health hazards. In this regard, the COVID‐19 pandemic presented the European Union (EU) with a severe challenge. We ask to what extent the border policies of EU member states during the pandemic supported regional ...
Christian Freudlsperger, Jana Lipps, Frank Schimmelfennig   +2 more
wiley   +1 more source

Pure erythroid leukaemia in early infancy: Diagnostic pitfalls and clinical challenges

British Journal of Haematology, EarlyView.
Riccardo De Carli, Baptiste Le Calvez, Elodie Lainey, Catherine Settegrana, Marion Strullu, Marlene Pouthier   +5 more
wiley   +1 more source

A Microkrystite from the Australasian Tektite/Microtektite Strewn Field

Meteoritics &Planetary Science, EarlyView.
Abstract Microkrystites are glassy impact spherules. They contain primary crystallites carrying information on the physical and chemical conditions prevailing during vaporization, melting, and ejection in large impact cratering events. We report on the geochemistry and mineralogy down to nanometer scale of the first microkrystite (ODP1144A,14) from the
Matteo Del Rio, Luigi Folco, Matteo Masotta, Ana Černok, Enrico Mugnaioli   +4 more
wiley   +1 more source

Prehospital whole blood transfusion versus component therapy—A scoping review

Transfusion, EarlyView.
Abstract Background Whole blood has gained a foothold over component therapy in civilian emergency care, especially in emergency departments. In a prehospital setting, whole blood might be the logistically easier alternative compared to component therapy. However, most previous studies have been conducted in the emergency room setting.
Laura Muurinen, Timo Jama, Tom Silfvast, Jouni Lauronen   +3 more
wiley   +1 more source

NAD replenishment restores mitochondrial function and thermogenesis in the brown adipose tissue of mice with obesity

The Journal of Physiology, EarlyView.
Abstract figure legend A high‐fat diet (HFD) induces brown adipose tissue (BAT) whitening, mitochondrial dysfunction (damaged cristae, fragmentation), reduced NAD+ levels and impaired thermogenesis, leading to lower energy expenditure and metabolic inflexibility.
Renata R. Braga, Matheus B. Rocha, Ana P. Morelli, Raul G. da Costa, Marcelo A. S. Mori, Adelino S. R. da Silva, José R. Pauli, Dennys E. Cintra, Eduardo R. Ropelle   +8 more
wiley   +1 more source

Association Between BMI and the Efficacy and Safety of CDK4/6 Inhibitors in HR+/HER2− Advanced Breast Cancer: A Multicenter Retrospective Propensity Score Matched Cohort Study (CAMELIA)

MedComm – Oncology, Volume 5, Issue 4, December 2026.
This multicenter real‐world study showed that higher BMI (≥ 25 kg/m2) was independently associated with improved PFS in patients with HR+/HER2− advanced breast cancer receiving CDK4/6 inhibitors. Safety outcomes were comparable between BMI groups, and the findings were consistent across alternative BMI thresholds, suggesting the potential prognostic ...
Min Tian, Yijia Hua, Qian Liu, Nan Jin, Xinyu Wu, Kun Wang, Min Yan, Tao Sun, Chunfang Hao, Yanxia Zhao, Wei Li, Xiang Huang, Yongmei Yin   +12 more
wiley   +1 more source

High‐throughput phenotyping for the prediction and quantification of flower‐related traits in sugarcane

The Plant Phenome Journal, Volume 9, Issue 1, December 2026.
Abstract Sugarcane (Saccharum spp.), a C4 plant, is a vital renewable biofuel and sugar source for industries worldwide. However, synchronizing flowering between parental lines often poses challenges for breeders, hindering effective crossbreeding efforts.
Paulo H. da Silva Santos, João R. Vieira Manechini, Carlos Augusto Dias Kanthack Jr., Mauro Alexandre Xavier, Samira Domingues Carlin, Dilermando Perecin, Thiago G. Marconi, Leandro G. Marconi, Elisson Antonio da Costa Romanel, Stephen Derek Jackson, Marcos. G. A. Landell, Luciana R. Pinto   +11 more
wiley   +1 more source

Total Neoadjuvant Treatment for Esophageal Adenocarcinoma With Oligometastases: TNT‐OES‐1 Trial

International Journal of Cancer, Volume 159, Issue 10, Page 2552-2561, 15 November 2026.
Total neoadjuvant therapy could combine the potentially strong systemic effect of FLOT chemotherapy with the good locoregional control of CROSS chemoradiotherapy. While total neoadjuvant therapy is increasingly used in rectal cancer, its potential in gastroesophageal cancer remains largely unexplored.
Charlène J. van der Zijden, Tamara J. Huizer, Ben M. Eyck, Ate van der Gaast, Leni van Doorn, Marjolein Y. V. Homs, J. Jan B. van Lanschot, Joost J. M. E. Nuyttens, Lindsey Oudijk, Manon C. W. Spaander, Bas P. L. Wijnhoven, Bianca Mostert, Sjoerd M. Lagarde   +12 more
wiley   +1 more source