Results 151 to 160 of about 113,946 (294)

Neurokinin‐1 receptor activation protects against cardiac fibrosis, inflammation and diastolic dysfunction in type 2 diabetic mice

British Journal of Pharmacology, EarlyView.
Background and Purpose The pathogenesis of type 2 diabetes mellitus (T2DM)‐induced cardiomyopathy involves cardiac fibrosis that leads to diastolic dysfunction. We established that replacement of lost substance P (SP) that occurs in T2DM reduces cardiac fibrosis and decreases inflammation in T2DM mice and non‐human primates.
Alexander Widiapradja, Heather Connery, Brody J. Helmick, Kallie J. Schafner, Vamsi Manchikalapudi, Hannah Horvath, Sophia Gugino, Tamas Kriska, Anja Herrnreiter, Evan DeVallance, William B. Campbell, Scott P. Levick   +11 more
wiley   +1 more source

Simulation-free spine palliative radiotherapy enabled by AI-adapted diagnostic CT. [PDF]

Med Phys
Han Y, Hanania AN, Siddiqui ZA, Ugarte V, Zhou B, Mohamed ASR, Pathak P, Hamstra DA, Sun B.   +8 more
europepmc   +1 more source

Variable‐Rate Texture Compression: Real‐Time Rendering with JPEG

Computer Graphics Forum, EarlyView.
Abstract Although variable‐rate compressed image formats such as JPEG are widely used to efficiently encode images, they have not found their way into real‐time rendering due to special requirements such as random access to individual texels. In this paper, we investigate the feasibility of variable‐rate texture compression on modern GPUs using the ...
Elias Kristmann, Michael Wimmer, Markus Schütz   +2 more
wiley   +1 more source

Comparative modulation of the gut microbiota by date-derived products and refined sugar: a 16S rRNA gene taxonomic profile in healthy rats. [PDF]

Front Microbiol
Alqurashi RM, Al-Mssallem MQ, Al-Majed AW, Almaghasla MI, Alarifi SN.   +4 more
europepmc   +1 more source

Establishment of Human Formative Pluripotent Stem Cell‐Like Cells Exhibiting Amniotic Differentiation Potentials

Cell Proliferation, EarlyView.
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang, Qizhi Wang, Yu Wu, Chen Gu, Mingfei Li, Yong Fan, Xiangjin Kang, Lei Li, Zheng Gao, Mingyan Hei, Jianqiao Liu, Lei Li   +11 more
wiley   +1 more source

A decade-long seamless-continuity daily L-band soil moisture product derived from SMOS observations since 2010. [PDF]

Sci Data
Bai Y, Jia L, Zhao T, Peng Z, Zheng J, Zheng C, Tang P, Shi J.   +7 more
europepmc   +1 more source

Integrated miRNA–mRNA Analysis Reveals Obesity‐Driven Regulatory Networks in Human Visceral Adipose Tissue With and Without Type 2 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Obesity is characterised by pathological alterations in visceral white adipose tissue (vWAT) that may contribute to the development of type 2 diabetes (T2D). While microRNAs (miRNAs) are key post‐transcriptional regulators, comprehensive human vWAT profiling across metabolic states remains limited.
Elsa Villa‐Fernández, Ana Victoria García, Laura Gallardo‐Nuell, Miguel García‐Villarino, Judit Fernández‐García, Aldara Martin Alonso, Claudia Lozano‐Aida, Lorena Suárez Gutiérrez, Pedro Pujante, Jessica Ares, Tomás González‐Vidal, Raquel Rodríguez Uría, Sandra Sanz Navarro, María Moreno Gijón, Lourdes María Sanz Álvarez, Estrella Olga Turienzo Santos, José Manuel Fernández‐Real, Mario Fernández Fraga, Elías Delgado, Carmen Lambert   +19 more
wiley   +1 more source

Adaptive bit placement for dual biometric using signature and finger print for DWT-DCT picture steganography. [PDF]

Sci Rep
Bhattacharya A, Welekar AR, Sarkar P, Bose R, Roy S, Mitra A.   +5 more
europepmc   +1 more source

Alteration in oral and non‐oral tissues in ligature‐induced periodontitis mice with the Alzheimer's disease risk factor APOE4

European Journal of Oral Sciences, EarlyView.
Abstract The APOE4 gene, particularly the ε4 allele, is linked to susceptibility to Alzheimer's disease, and periodontitis can cause pathological changes in multiple organs, but combined effects of these conditions and the impact of tumor necrosis factor (TNF)‐α regulation on the combined effects remain unclear.
Ae Ri Kim, Yun‐Jung Yoo, Eun‐Jung Bak   +2 more
wiley   +1 more source

Refined trajectory smoothing and deep learning classification of human sperm motility. [PDF]

Hum Reprod
Shahali S, Mortimer ST, McLachlan R, O'Bryan MK, Zander-Fox D, Mortimer D, Ackermann K, Neild A, Nosrati R.   +8 more
europepmc   +1 more source