Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio +12 more
wiley +1 more source
Fibulin 2 Deficiency Drives Epigenetic Hypertension. [PDF]
Han X, Sun Z.
europepmc +1 more source
Small protein MtrR is a regulator of the Mtr methyltransferase complex in Methanosarcina mazei. It binds specifically to the MtrA subunit and modulates Mtr activity in response to hydrogen (H2) availability. Deleting mtrR impairs growth in the presence but not absence of H2, indicating its role in directing methyl transfer toward an energy‐conserving ...
Tim Habenicht +6 more
wiley +1 more source
The influence of ocular parameters on intraocular pressure values measured by different devices and the development of an optimized prediction model in a myopic population. [PDF]
Gan W +5 more
europepmc +1 more source
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur +6 more
wiley +1 more source
Dynamic and differential renal cortical cell-specific mitochondrial metabolism in response to fasting. [PDF]
Feola K +10 more
europepmc +1 more source
The Complexity of Expressions of Approval—One Aspect of Relational Practice in Diverse Workplaces
ABSTRACT The majority of workplaces in Aotearoa New Zealand typically include team members from diverse cultural backgrounds, and yet an orientation to majority group norms (in this case, Pākehā) still dominates. In this article, we draw on naturally occurring workplace talk in a range of workplaces to explore both dominant group practices and norms ...
Janet Holmes, Bernadette Vine
wiley +1 more source
ICG-001 Provides Cardioprotection Against Doxorubicin-Induced Cardiotoxicity and Enhances Cancer Cytotoxicity. [PDF]
Wu B +19 more
europepmc +1 more source
ABSTRACT This study examined English vocabulary learning by using three types of flashcards: paper flashcards, non‐gamified mobile application (app) flashcards (i.e., digital flashcards), and gamified mobile app flashcards (i.e., gamified flashcards) in a privately owned language institute in Iran.
Ali Soyoof +3 more
wiley +1 more source
Genetically Optimized Modular Neural Networks for Precision Lung Cancer Diagnosis: Exploratory Study of Novel Approach. [PDF]
Agrawal VL +5 more
europepmc +1 more source

