Results 41 to 50 of about 74,286 (216)

The Bitter Taste of Brazil's Temporary Import Ban on Robusta Coffee

Agribusiness, EarlyView.
ABSTRACT Brazil, a leading Robusta coffee producer and exporter, faced a significant drought in 2016–2017, which drastically reduced production and depleted stocks. Consequently, Brazil temporarily permitted the import of one million 60‐kg bags of Robusta coffee in the spring 2017. An import ban was imposed shortly afterward due to lobbying by domestic
Hanifi Otgun, John Beghin, Fernando Maximiliano   +2 more
wiley   +1 more source

Multi-GPU implementation of a VMAT treatment plan optimization algorithm

, 2015
VMAT optimization is a computationally challenging problem due to its large data size, high degrees of freedom, and many hardware constraints. High-performance graphics processing units have been used to speed up the computations.
Folkerts, Michael, Jia, Xun, Jiang, Steve B., Peng, Fei, Tan, Jun, Tian, Zhen   +5 more
core   +1 more source

Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt

Annals of Neurology, EarlyView.
As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez, Cyril Pottier, Aleksandra Beric, Daniel Western, Muhammad Ali, Carlos Cruchaga   +5 more
wiley   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

A Bifunctional Cytochrome P450 Enzyme Catalyzes Hydroxylation and Aryl‐Aryl Ether Formation in the Biosynthesis of Emestrin

Chemistry – A European Journal, EarlyView.
Conversion of emestrin J (5) to emestrin (1) by three P450 enzymes from the cluster (eme) in Emericella quadrilineata. EmeO acts as a bifunctional enzyme for the construction of the 15‐membered lactone ring via an aryl‐aryl ether bond formation and simultaneous hydroxylation between phenolic and nonphenolic aromatic rings, while EmeE and EmeR install ...
Yu‐Chuan Chen, Jing‐Jing Wu, Ming‐Hua Chen, Shu‐Ming Li   +3 more
wiley   +1 more source

The Antitrust of Reputation Mechanisms: Institutional Economics and Concerted Refusals to Deal [PDF]

, 2009
An agreement among competitors to refuse to deal with another party is traditionally per se illegal under the antitrust laws. But coordinated refusals to deal are often necessary to punish wrongdoers, and thus to deter undesirable behavior that state ...
Richman, Barak D.
core   +1 more source

First experiences with the ATLAS Pixel Detector Control System at the Combined Test Beam 2004

, 2005
Detector control systems (DCS) include the read out, control and supervision of hardware devices as well as the monitoring of external systems like cooling system and the processing of control data.
Imhäuser, Joachim Schultes, Karl-Heinz Becks, Martin Imhäuser, Peter Mättig, Susanne Kersten, Tobias Henß   +6 more
core   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

HILT : High-Level Thesaurus Project. Phase IV and Embedding Project Extension : Final Report [PDF]

, 2009
Ensuring that Higher Education (HE) and Further Education (FE) users of the JISC IE can find appropriate learning, research and information resources by subject search and browse in an environment where most national and institutional service providers -
Joseph, Anu, McCulloch, Emma, Nicholson, Dennis   +2 more
core  

NIKEL: Electronics and data acquisition for kilopixels kinetic inductance camera

, 2012
A prototype of digital frequency multiplexing electronics allowing the real time monitoring of microwave kinetic inductance detector (MKIDs) arrays for mm-wave astronomy has been developed.
, , A Benoit, A Monfardini, A. Monfardini ., C Vescovi, G. Comoretto, J F Macias-Perez, J L Bouly, J. Volder, L Gallin-Martel, M Calvo, O Bourrion, O. Bourrion ., S. Doyle   +14 more
core   +4 more sources