Results 51 to 60 of about 64,857 (161)

Irradiated Liver Cancer Cell Vaccine Transfected With GM‐CSF Induces Specific and Long‐Lasting Anti‐tumour Immunity Through the Synergistic Effect of Oxidised mtDNA and GM‐CSF

Cell Proliferation, EarlyView.
Song et al. developed an mGM‐CSF‐loaded, liver cancer cell‐based vaccine that potently activated dendritic cells and elicited tumour‐specific T cell responses. Mechanistically, radiation‐induced oxidative damage to mitochondrial DNA in cancer cells triggers the cGAS‐STING pathway in DCs, which synergizes with mGM‐CSF‐driven JAK2‐STAT3 signalling to ...
Zhiruo Song, Yujie Jiang, Yu Zhang, Danyi Ao, Chunjun Ye, Xiya Huang, Yingqiong Zhou, Hanle Yang, Ruolan Xia, Jiayuan Ai, Dandan Wan, Aiping Tong, Yuquan Wei, Xuemei He, Aqu Alu, Xiawei Wei   +15 more
wiley   +1 more source

Fundamental Conditions for N-th Order Accurate Lattice Boltzmann Models

, 2007
In this paper, we theoretically prove a set of fundamental conditions pertaining discrete velocity sets and corresponding weights. These conditions provide sufficient conditions for a priori formulation of lattice Boltzmann models that automatically ...
Agarwal, Alexander, Benzi, Bishop, Cercignani, Chapman, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Frisch, Frisch, Gad-el-Hak, Hudong Chen, Qian, Sbragaglia, Schwarzenberger, Shan, Shan, Teixeira, Vainshtein, Watari, Wolfram, Xiaowen Shan, Zhang   +28 more
core   +1 more source

Postprandial Glucagon Action in the Human Brain

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Elevated fasting glucagon is linked to hyperglycemia, but postprandial glucagon effects are less understood. Recent evidence suggests metabolic benefits of rising glucagon after oral glucose intake, potentially impacting brain‐mediated whole‐body metabolism.
Robert Wagner, Stephanie Kullmann, Julia Hummel, Katsiaryna Prystupa, Elena Hosenfeld, Ralf Veit, Andreas L. Birkenfeld, Hans‐Ulrich Häring, Hubert Preissl, Andreas Fritsche, Andreas Peter, Martin Heni   +11 more
wiley   +1 more source

Global Citizenship in Clinical Training: A Qualitative Study Evaluating a Co‐Creation Approach to Community Oral Health Interventions

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction Oral health plays a crucial role in overall well‐being, impacting general health, psychological health and quality of life. Vulnerable groups often face higher rates of oral health problems, exacerbating inequalities. This study evaluates the effectiveness of student‐delivered oral health interventions with these groups using a co‐
Mahdi Hussaini, Andrea Rodriguez, Clement Seeballuck   +2 more
wiley   +1 more source

DDC Lesson Plan [PDF]

, 2023
This lesson is designed as a one-shot lecture to teach first-year library students how to classify under the Dewey Decimal Classification system. It is designed for students with little to no prior knowledge of the DDC, but can also serve as a useful refresher for those with prior knowledge.
openaire  

Use of a 3D‐printed custom‐designed tracheostomy tube to stabilise a permanent tracheostoma in a 25‐year‐old Icelandic mare

Equine Veterinary Education, EarlyView.
Summary A 25‐year‐old Icelandic mare diagnosed with bilateral temporohyoid‐osteoarthropathy, moderate pharyngeal instability and bilateral laryngeal paralysis was presented because of intermittent stridor and dyspnoea worsening during exercise. As a previous ceratohyoidectomy had not improved these symptoms substantially, a permanent tracheostomy was ...
D. C. Debald, J. P. Schramel, E. Haltmayer, N. M. Biermann   +3 more
wiley   +1 more source

Mechanical stiffness orchestrates distinct regulation of MRTFs and YAP/TAZ transcriptional cofactors in hepatocytes

The FEBS Journal, EarlyView.
MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz, Daniel Pérez‐Calixto, Jorge Carretero‐Ortega, Aida Gabriela Guzman‐López, Diana Cristina Pinto‐Dueñas, Mariana Hernández‐Juárez, Alejandra Jiménez‐Escobar, Adriana Rodríguez‐Hernández, Beatriz Díaz‐Bello, Nathalia Serna‐Márquez, Miguel Ángel Peña‐Rico, Laura Gómez‐Romero, Francisco Gabriel Vázquez‐Cuevas, Genaro Vázquez‐Victorio   +13 more
wiley   +1 more source

Ddc Report 2017 Of Wdcc

, 2018
This report provides statistics on the data download from the Reference Data Archive for climate model output hosted at the IPCC DDC at WDCC/DKRZ (http://ipcc.wdc-climate.de) for 2017eng.
Stockhause, Martina, Lautenschlager, Michael   +1 more
openaire   +1 more source

Ecological restoration hierarchy as a lens to reveal the foundational economic and legal structures impeding restoration

Restoration Ecology, EarlyView.
Abstract Introduction Biodiversity loss is accelerating due to habitat destruction, economic expansion, and insufficient conservation efforts. Traditional mitigation strategies, which focus on minimizing harm rather than reversing damage, are inadequate for achieving net biodiversity gain. Objectives This article introduces the restoration hierarchy, a
Niko Soininen, Suvi‐Tuuli Puharinen, Antti Iho, Saija Koljonen, Janne Artell, Kimmo Tolonen, Antti Belinskij   +6 more
wiley   +1 more source

Hubungan Persepsi Pemustaka tentang Sistem Klasifikasi Dewey Decimal Classification (DDC) dengan Pemanfaatan Sistem telusur Elektronik pada Perpustakaan Sekolah Tinggi Pariwisata Bandung [PDF]

, 2015
Penelitian ini dilatarbelakangi oleh situasi pemustaka perpustakaan perguruan tinggi yang kurang memanfaatkan sistem telusur elektronik (OPAC – Online Public Access Catalog) yang disediakan oleh perpustakaan untuk melakukan penelusuran koleksi ...
Hastari, Nia
core