Results 1 to 10 of about 2,076 (67)

Methylglyoxal Affects Dopamine Homeostasis in SH-SY5Y Cells Through the Modulation of miR-190a and miR-214. [PDF]

FASEB J
In SH‐SY5Y cells, Methylglyoxal (MGO) reduces the intracellular dopamine content, up‐regulating the expression of proteins that modulate dopamine amount (MAO‐B, COMT, and α‐Syn). The MGO‐induced increase of COMT and α‐Syn expression is mediated by the reduction of miR‐214 and miR‐190a levels.
Croce A, Mirra P, Pignalosa FC, Zatterale F, Prevenzano I, Conza D, Ulianich L, Miele C, Beguinot F, Fiory F.   +9 more
europepmc   +2 more sources

Prediction of lymph node metastasis in non-small cell lung cancer and its correlation with Ki-67 expression: a comparative study between intravoxel incoherent motion imaging and ¹⁸F-FDG PET. [PDF]

BMC Med Imaging
Wei W, Chen Q, Meng N, Wang X, Liu Y, Zhang J, Wu Y, Pan J, Huang Z, Yang Y, Wang Z, Liu Q, Fu F, Wang M.   +13 more
europepmc   +1 more source

Loss of β-catenin in cholangiocytes promotes hepatocyte reprogramming and vascular remodeling during murine cholestasis. [PDF]

Cell Commun Signal
Carson M, Fornsaglio J, Case Iv R, Aggarwal R, Meadows V, Kim CK, Molina L, Cornuet P, Liu JJ, Liu S, Nejak-Bowen K.   +10 more
europepmc   +1 more source

DNA Methylation Fine-Tunes Light- and Hormone-Responsive Growth Plasticity in Arabidopsis Seedlings. [PDF]

Int J Mol Sci
Talarico E, Greco E, Chiappetta A, Araniti F, Bruno L.   +4 more
europepmc   +1 more source

Protocol for a phase 2, partially blinded, randomized trial assessing the safety and efficacy of sorfequiline or bedaquiline in combination with pretomanid and linezolid in adult participants with newly diagnosed, drug-sensitive, smear-positive pulmonary tuberculosis (NC-009). [PDF]

Trials
Olugbosi M, Beumont M, Lombard L, Nedelman J, Timm J, Black T, Bruning-Barry R, Hickman D, Lombardi A, Betteridge M, Egizi E, Marcopulos L, Henderson J, Seidel S, Foraida S, Benhayoun M, Sun E.   +16 more
europepmc   +1 more source

Multi-omics exploration demonstrated the antidepressant effects of chrysophanol on diabetes-depression comorbidity rats via inflammatory, and neurodegenerative axes. [PDF]

Sci Rep
Hu XJ, Ge D, Ma XL, Yang Y.
europepmc   +1 more source

Multi-stage decimation with hybrid CIC-polyphase filtering for IoT gateway sample rate conversion. [PDF]

Sci Rep
Pinjerla S, Rao SS, Reddy PC.
europepmc   +1 more source

The RPA-binding domain and the KKRK motif in Rad26ATRIP cooperate at the perturbed DNA replication fork for initiating checkpoint signalling. [PDF]

PLoS Genet
Xu YJ, Gao A, Dev K, Zheng Y, Alyahya MY, Pasam S, Kaur G, Zhou C.   +7 more
europepmc   +1 more source

(±)-2-Cyclohexyl-5-methoxy-2H-chromene, a Synthetic 5-Methoxyflavone Derivative, Is a Selective DNA Polymerase-β Inhibitor with Neuroprotective Activity against β-Amyloid Toxicity. [PDF]

ACS Chem Neurosci
Guccione S, Merlo S, Tagliapietra S, Pappalardo M, Binello A, Barge A, Basile L, Sortino MA, Cravotto G, Copani A.   +9 more
europepmc   +1 more source

The CRISPR-Cas9 knockout DDC SH-SY5Y in vitro model for AADC deficiency provides insight into the pathogenicity of R347Q and L353P variants: a cross-sectional structural and functional analysis. [PDF]

FEBS J
Carmona-Carmona CA, Bisello G, Franchini R, Lunardi G, Galavotti R, Perduca M, Ribeiro RP, Belviso BD, Giorgetti A, Caliandro R, Lievens PM, Bertoldi M.   +11 more
europepmc   +1 more source