Results 31 to 40 of about 465,829 (92)

Protocol for a phase 2, partially blinded, randomized trial assessing the safety and efficacy of sorfequiline or bedaquiline in combination with pretomanid and linezolid in adult participants with newly diagnosed, drug-sensitive, smear-positive pulmonary tuberculosis (NC-009). [PDF]

open access: yesTrials
Olugbosi M   +16 more
europepmc   +1 more source

(±)-2-Cyclohexyl-5-methoxy-2H-chromene, a Synthetic 5-Methoxyflavone Derivative, Is a Selective DNA Polymerase-β Inhibitor with Neuroprotective Activity against β-Amyloid Toxicity. [PDF]

open access: yesACS Chem Neurosci
Guccione S   +9 more
europepmc   +1 more source

The CRISPR-Cas9 knockout DDC SH-SY5Y in vitro model for AADC deficiency provides insight into the pathogenicity of R347Q and L353P variants: a cross-sectional structural and functional analysis. [PDF]

open access: yesFEBS J
Carmona-Carmona CA   +11 more
europepmc   +1 more source

Ligase 3 prevents oxidative strand break-induced mitochondrial DNA loss but is not essential for replicative circularization. [PDF]

open access: yesNucleic Acids Res
Trombly G   +9 more
europepmc   +1 more source

A phase I study to evaluate the effect of high-dose carbidopa on levodopa pharmacokinetics. [PDF]

open access: yesFront Pharmacol
Hayashi A   +7 more
europepmc   +1 more source

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