Results 161 to 170 of about 66,929 (277)

CDK7 as a Potential Exploratory Biomarker for Distinguishing Acute Myocardial Infarction Subtypes via DDR Pathways: Evidence From a Bangladeshi Cohort. [PDF]

Clin Cardiol
Ripon RH, Zahin H, Noman AA, Saba AA, Sayem M, Nabi AHMN, Yasmin T.   +6 more
europepmc   +1 more source

Losartan Enhances Radiosensitivity by Reversing Immunosuppressive Tumor Microenvironment Induced by Radiotherapy in TNBC

Cancer Science, Volume 117, Issue 7, Page 1795-1812, July 2026.
Our study demonstrates that the angiotensin receptor blocker losartan enhances the efficacy of radiotherapy in triple‐negative breast cancer by reversing the immunosuppressive tumor microenvironment. Losartan reprograms tumor‐associated macrophages, inhibits myeloid‐derived suppressor cell function, and boosts CD8+ T‐cell activity.
Xu Wang, Cuiwei Liu, Zihan Xia, Ting Hu, Yuting Li, Dan Han, Yunjie Song, Yuxi Ma, Yanxia Zhao   +8 more
wiley   +1 more source

Molecular landscape and clinical translation of DNA damage response alterations in solid tumors: A pan-cancer perspective on precision oncology. [PDF]

Neoplasia
Zhu H, Shao J, Wang Y, Gu C, Liu J.
europepmc   +1 more source

In Silico Drug Repositioning Identifies SYK Kinase Inhibitors as Potential Neuroprotective Agents for Ataxia–Telangiectasia

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
Repositioning of vemurafenib and palbociclib as spleen tyrosine kinase inhibitors for the treatment of neuroinflammation in Ataxia–Telangiectasia. ABSTRACT Ataxia–Telangiectasia (AT) is a rare neurodegenerative disorder characterized by progressive neuronal loss and chronic neuroinflammation.
Alessia Romano, Rocco Buccheri, Chiara Zagni, Antonio Rescifina   +3 more
wiley   +1 more source

Merkel Cell Polyomavirus and DNA Damage Response (DDR): Transcriptional Analysis of DDR Pathways in the Context of Merkel Cell Carcinoma. [PDF]

Cancers (Basel)
Messina S, Mallardo D, Ferlosio A, Festino L, Trojaniello C, Di Trolio R, Ciotti M, Ascierto PA, Pietropaolo V, Passerini S.   +9 more
europepmc   +1 more source

‘ZWISCHEN DEN ZEILEN’: A CLOSE READING OF STEFANIE‐LAHYA AUKONGO'S NEUROQUEER POETRY

German Life and Letters, Volume 79, Issue 3, Page 365-383, July 2026.
ABSTRACT This article analyses the multimodal poetry of Stefanie‐Lahya Aukongo (b. 1978) through the framework of neuroqueer theory (e.g. Nick Walker, M. Remi Yergeau), showing how her poetic practice exposes and destabilises socially constructed norms of neurotypicality.
Catherine Smale
wiley   +1 more source

Long-Term PET-Nanoplastic Exposure Alters DNA Damage Response Capacity in BEAS-2B Human Bronchial Epithelial Cells. [PDF]

Int J Mol Sci
Morataya-Reyes M, Villacorta A, Egea R, Martín-Pérez J, Gutiérrez-García J, Pastor S, Marcos R, Hernández A.   +7 more
europepmc   +1 more source

Publizistik und Journalismus in der DDR Acht Beiträge Zum Gedenken an Elisabeth Löckenhoff [PDF]

Intro -- Zum Gedenken -- Inhalt -- Vorwort -- Einführung -- Elisabeth Löckenhoff im Institut für Publizistik der Freien Universität Berlin (1952-1985) -- Zur wissenschaftlichen Behandlung der DDR-Massenmedien in der Bundesrepublik Deutschland ...
Löckenhoff, Elisabeth., Geserick, Rolf., Kutsch, Arnulf.   +2 more
core  

ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

International Journal of Cancer, Volume 158, Issue 12, Page 3173-3186, 15 June 2026.
What's new? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte, Hossam Eldesouky, Julia Puchan, Sercan Öz, Elena Everatt, Ashish Goyal, Gianluca Sigismondo, Udo Oppermann, Christoph Plass, Dieter Weichenhan, Ali Bakr   +10 more
wiley   +1 more source

Diversity of Factors Associated with Physical Inactivity in Patients with Asthma Based on Activity Intensity. [PDF]

J Clin Med
Murakawa K, Hirano T, Doi K, Fukatsu-Chikumoto A, Yamaji Y, Iwamoto H, Miyamoto S, Higaki N, Amano Y, Anabuki K, Yamane M, Oishi K, Asami-Noyama M, Edakuni N, Kakugawa T, Matsunaga K.   +15 more
europepmc   +1 more source