Results 161 to 170 of about 32,248 (253)
This review elucidates how lactylation, a novel histone modification driven by lactate, regulates colorectal cancer pathogenesis. We summarize its roles in tumor progression, metastasis, stemness, immunosuppression, and therapy resistance, and discusses the promising therapeutic strategies of targeting the lactylation pathway.
Shuilan Yao +4 more
wiley +1 more source
Construction of a Lysine Lactylation- and DNA Damage Repair-Related Gene Signature to Predict the Prognosis and Drug Sensitivity of Breast Cancer Patients. [PDF]
Zhu L +7 more
europepmc +1 more source
EOPC is a distinct clinicopathological entity separable from SOPC, differing fundamentally in genetic susceptibility, TMPRSS2:ERG fusion frequency, and survival outcomes. Although research remains nascent, this review provides the first comprehensive synthesis of current evidence, offering a critical foundation to guide future investigations into this ...
Xingyu Xiong +8 more
wiley +1 more source
Respiratory Models Reveal DNA Damage Response Modulation by Merkel Cell Polyomavirus. [PDF]
Passerini S +7 more
europepmc +1 more source
Abstract Background Rapid technological innovation in diagnostic imaging requires timely, evidence‐based safety and quality assessment to ensure optimal patient care. This study evaluates a novel multi‐modality extremity imaging system (OXOS MC2) designed for deployment in remote and austere environments.
Xiangyu Yang +6 more
wiley +1 more source
Die katalytische Reaktion von alkylsubstituierten Heterozyklen mit NO
Eberhard Fischer
doaj +1 more source
Systems Biology and Multi-Omics Determinants of Response to Bladder-Preserving Trimodality Therapy in Muscle-Invasive Bladder Cancer. [PDF]
Schițcu VH +6 more
europepmc +1 more source
Biomaterial‐integrated electroporation establishes a programmable therapeutic interface that coordinates electric‐field modulation, transient or irreversible membrane permeabilization, cargo stabilization, and immune remodeling. This Review highlights how nanocarriers, hydrogels, and bioelectronic interfaces expand electroporation from conventional ...
Binbin Ji +13 more
wiley +1 more source

