Results 151 to 160 of about 208,136 (294)

Dual Targeting of DNA and EGFR by ZYH005 Induces DNA Damage and Mitotic Catastrophe in Glioblastoma

open access: yesMedComm, Volume 7, Issue 4, April 2026.
ZYH005 exerts potent anti‐glioblastoma activity through a dual mechanism: intercalation‐mediated DNA damage and targeted inhibition of EGFR, leading to cell cycle arrest and mitotic catastrophe. ABSTRACT Glioblastoma multiforme (GBM) is an aggressive, therapy‐resistant brain tumor with limited treatment options.
Jianzheng Huang   +12 more
wiley   +1 more source

Recent Advances in Hafnium Oxide Nanomaterials: From Controlled Synthesis, Structure, and Surface Engineering to Biomedical Applications

open access: yesRare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Hafnium oxide (HfO2) nanoparticles (NPs), derived from a rare‐metal element, have gained increasing attention as a versatile class of functional nanostructures with unique optical, dielectric, and surface properties that enable diverse biomedical applications. As a representative rare‐metal oxide, HfO2 NPs with well‐defined architectures offer
Mothana Hussein Tarawneh   +8 more
wiley   +1 more source

Construction of CoP/Mn2P Heterojunctions via One‐Step Phosphorization Coupled With Hollow Hard Carbon Spheres as Supports: Enabling Ultrastable Long‐Cycle Sodium‐Ion Anodes Over a Wide Temperature Range

open access: yesRare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Driven by global energy transition and sustainability, sodium‐ion batteries (SIBs) have emerged as key alternatives to lithium‐ion batteries for low‐to‐medium energy storage, because of abundant sodium resources and low cost. However, their commercialization is hindered by the lack of anodes with high capacity, fast kinetics, and long‐term ...
Shuang‐Lin Cai   +13 more
wiley   +1 more source

Reply to Comment by Hetényi and Cattin on: “Raising the Roof of the World: Intra‐Crustal Asian Mantle Supports the Himalayan‐Tibetan Orogen”

open access: yesTectonics, Volume 45, Issue 4, April 2026.
Abstract We welcome the critique of Hetényi and Cattin on Sternai et al. (2025, https://doi.org/10.1029/2025tc009057), as it brings to light evaluative issues that require clarification and offers an opportunity to articulate more clearly how our work advances understanding of Himalayan‐Tibetan geodynamics.
P. Sternai   +11 more
wiley   +1 more source

Double‐Pronged NAD Preservation: Delaying Cellular Senescence and Initiating Musculoskeletal Regeneration

open access: yesAging Cell, Volume 25, Issue 4, April 2026.
A novel drug combination (NMN + API) promotes musculoskeletal regeneration in aging. By boosting NAD+, it activates SIRT3 to suppress cellular senescence and enhance differentiation into chondrocytes, osteoblasts, and myocytes. Oral administration reshapes the gut microbiota, increasing production of the anti‐aging metabolite PHS.
Jianfeng Yu   +12 more
wiley   +1 more source

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