Results 151 to 160 of about 208,136 (294)
Dual Targeting of DNA and EGFR by ZYH005 Induces DNA Damage and Mitotic Catastrophe in Glioblastoma
ZYH005 exerts potent anti‐glioblastoma activity through a dual mechanism: intercalation‐mediated DNA damage and targeted inhibition of EGFR, leading to cell cycle arrest and mitotic catastrophe. ABSTRACT Glioblastoma multiforme (GBM) is an aggressive, therapy‐resistant brain tumor with limited treatment options.
Jianzheng Huang +12 more
wiley +1 more source
16/2006: Wie der Marxismus-Leninismus aus den Universitäten der DDR verschwand. Das Beispiel Jena
Michael Ploenus
openalex +1 more source
ABSTRACT Hafnium oxide (HfO2) nanoparticles (NPs), derived from a rare‐metal element, have gained increasing attention as a versatile class of functional nanostructures with unique optical, dielectric, and surface properties that enable diverse biomedical applications. As a representative rare‐metal oxide, HfO2 NPs with well‐defined architectures offer
Mothana Hussein Tarawneh +8 more
wiley +1 more source
Neues Verfahren zur Darstellung α-substituierter Pyrazolon-(5)-trimethin-oxonole
Bodo Hirsch, Eckhart Förster
doaj +1 more source
An ATM-AMPK-Wip1 feedback loop governing DNA-damage signaling and tumor stress responses. [PDF]
Gupta S, Panda PK.
europepmc +1 more source
ABSTRACT Driven by global energy transition and sustainability, sodium‐ion batteries (SIBs) have emerged as key alternatives to lithium‐ion batteries for low‐to‐medium energy storage, because of abundant sodium resources and low cost. However, their commercialization is hindered by the lack of anodes with high capacity, fast kinetics, and long‐term ...
Shuang‐Lin Cai +13 more
wiley +1 more source
Abstract We welcome the critique of Hetényi and Cattin on Sternai et al. (2025, https://doi.org/10.1029/2025tc009057), as it brings to light evaluative issues that require clarification and offers an opportunity to articulate more clearly how our work advances understanding of Himalayan‐Tibetan geodynamics.
P. Sternai +11 more
wiley +1 more source
The DNA damage response pathway is required for multiciliated cell differentiation. [PDF]
Jewett CE, Holland AJ, Pearson CG.
europepmc +1 more source
A novel drug combination (NMN + API) promotes musculoskeletal regeneration in aging. By boosting NAD+, it activates SIRT3 to suppress cellular senescence and enhance differentiation into chondrocytes, osteoblasts, and myocytes. Oral administration reshapes the gut microbiota, increasing production of the anti‐aging metabolite PHS.
Jianfeng Yu +12 more
wiley +1 more source

