Results 141 to 150 of about 208,136 (294)

Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan   +12 more
wiley   +1 more source

Anne Frank in de DDR en Rusland

open access: diamond, 2019
Lut Missinne, Irina Michajlova
openalex   +1 more source

Fuel Consumption and Emissions Reductions of Hybrid Electric Regional‐Haul Trucks Equipped with a High‐Pressure Direct Injection Natural Gas Engine in Real‐World Driving Conditions

open access: yesEnergy Technology, Volume 14, Issue 4, April 2026.
Integrating powertrain electrification with efficient engines using low‐carbon fuels like natural gas (NG) improves energy conversion efficiency and mitigates greenhouse gas (GHG) emissions in heavy‐duty (HD) trucks. High‐pressure direct injection (HPDI) NG engines, using less than 5% diesel (energy basis) as pilot fuel, offer diesel‐like efficiency ...
Sina Moghadasi   +3 more
wiley   +1 more source

The Nexus of Stemness, Telomere Stability, and Metabolic Reprogramming in Glioblastoma: Foundations of Tumor Persistence and Targets for Intervention

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Integrated schematic depicting the interplay between glioma stem‐like cells, telomere maintenance mechanisms, and metabolic reprogramming in shaping immune suppression and therapeutic resistance in glioblastoma . ABSTRACT Glioblastoma (GBM) is a highly aggressive, therapy‐resistant brain tumor with inevitable recurrence despite maximal multimodal ...
Ji‐Yong Sung, Kihwan Hwang
wiley   +1 more source

Antibody–Drug Conjugates in Oncology: Principles, Clinical Development, and Future Directions

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Antibody–drug conjugates integrate antibody targeting with potent cytotoxic payloads to enable precision cancer therapy. Their clinical performance depends on coordinated optimization of engineering design, tumor antigen biology, and treatment strategy. Lessons from uro‐oncological malignancies illustrate how ADCs can be effectively developed, combined,
Bisheng Cheng   +6 more
wiley   +1 more source

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