Results 31 to 40 of about 208,136 (294)
Design of a digital NHit trigger circuit for nuclear and particle physics experiment
Dianzi Jishu Yingyong, 2023 In nuclear and particle physics experiments, due to the influence of the experimental background and detector noise, the experiment needs to pick out valid physical events by the trigger selection, and eliminate the background noise.
Liu Shangming +3 more
doaj +1 more source
Risks from low dose/dose rate radiation: what an understanding of DNA damage response mechanisms can tell us [PDF]
, 2009 The DNA damage response (DDR) mechanisms represent a vital line of defense against exogenous and endogenous DNA damage to enhance two distinct outcomes, survival and the maintenance of genomic stability. The latter is critical for cancer avoidance.
Jeggo, Peggy A.
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Active and Passive Electronic Components, 1988 Experimental results concerning the dependence of the sheet resistivity and the noise coefficient on the grain size and the volume fraction, respectively, of the metallic-like component in Bi2Ru2O7-based thick-film resistors are presented.
F. Müller, M. Wolf
doaj +1 more source
Lea, 2023 Il racconto di Christa Wolf Neue Lebensansichten eines Katers viene solitamente interpretato come una satira socio-scientifica rivolta contro le aspirazioni tecnocratiche della DDR e all'interno della quale le donne non rivestono che un ruolo marginale ...
Carmen Mitidieri
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Barreras psicosociales para la vinculación laboral de excombatientes
Revista Kavilando, 2021 En el marco de la firma del acuerdo de paz entre las FARC-EP y el gobierno colombiano, surge la inquietud de cómo se están dando los procesos de inclusión laboral de los desmovilizados y qué papel juegan las Barreras psicosociales para la paz, por lo que
Glenda C Soto Chima +2 more
doaj
REPENSER LE PROCESSUS DDR EN RÉPUBLIQUE DÉMOCRATIQUE DU CONGO A L’HEURE DE L’ALTERNANCE POLITIQUE [PDF]
Cahiers Africains des Droits de l’Homme et de la Démocratie ainsi que du Développement Durable, 2023 Le présent article revisite le processus DDR - Désarmement, Démobilisation et Réinsertion-, en République Démocratique du Congo, au moment où, dans le contexte actuel de l’alternance politique, intervenue à la suite des dernières élections de 2018, il ...
Nelson PALUKU SYAYIPUMA
doaj
The Distance Duality Relation from Strong Gravitational Lensing
, 2016 Under very general assumptions of metric theory of spacetime, photons traveling along null geodesics and photon number conservation, two observable concepts of cosmic distance, i.e.
Biesiada, Marek +5 more
core +1 more source
Transient PP2A inhibition alleviates normal tissue stem cell susceptibility to cell death during radiotherapy [PDF]
, 2018 Unintended outcomes of cancer therapy include ionizing radiation (IR)-induced stem cell depletion, diminished regenerative capacity, and accelerated aging.
Fabbrizi, Maria Rita +6 more
core +3 more sources