Results 41 to 50 of about 32,248 (253)
Erinnerungen an Begegnungen mit Germanisten aus den Ostblockstaaten während der kommunistischen Zeit
Convivium, 2009 Der Autor hatte schon während seiner Marburger Zeit ab 1962 germanistische Sprachwissenschaftler(innen) aus den kommunistischen Oststaaten kennengelernt und baute diese Beziehungen nach seiner Berufung als Ordinarius an die Universität Wien 1971/72 aus ...
Peter Wiesinger
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Advanced Science, EarlyView.Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin +20 more
wiley +1 more source
Straffrätt och kriminalpolitik i DDR
Nordisk Tidsskrift for Kriminalvidenskab, 1988 Intet ...
Erich Buchholz
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Advanced Science, EarlyView.Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang +8 more
wiley +1 more source
Ahnung? Erkenntnis? Antizipatorisches in der DDR-Lyrik der Vor-Wende-Zeit
Internationale Zeitschrift für Kulturkomparatistik, 2019 The ability of poetry – on the basis of its generic capability to bring together playfulness and awareness, an anticipated future (Ahnung) and the present – has had consequences for the history of German poetry insofar as poetry could function as a ...
Peter Geist
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PeriodIcon, 2023 To this day, GDR magazines have hardly been found worthy of a closer analytical look. As the present essay will argue, they have been treated primarily as containers for propaganda. In the introduction to this special issue on GDR magazines, the authors discuss why this has been the case so far and why GDR magazines in particular would be worth an ...
Vincent Fröhlich, Madleen Podewski
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Advanced Science, EarlyView.Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang +11 more
wiley +1 more source
Archives of Acoustics, 2016 Theoretical fundamentals are derived for measuring the four-pole para-meters of vibration isolators at real loads. Since the dynamic properties of rubber springs depend on the initial load, the vibration force and velocity are measured on the isolator ...
G. MELTZER, R. MELZIG-THIEL
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Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration
Advanced Science, EarlyView.This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya +10 more
wiley +1 more source
Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy
Advanced Science, EarlyView.A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li +11 more
wiley +1 more source