Results 101 to 110 of about 58,730,988 (246)

The use of neural networks for fitting complex kinetic data [PDF]

open access: yes, 1996
Congrès ESCAPE-3: European Symposium on Computer Aided Process Engineering n.3, Graz , Autriche, 1993In this paper the use of neural networks for fitting complex kinetic data is discussed.
Zaldívar, J.M.   +3 more
core   +1 more source

1‐Azabicyclo[1.1.0]butanes (ABBs) on the Map: Mechanistic Pathways for Catalytic Ring Opening and Functionalizations

open access: yesAngewandte Chemie, EarlyView.
Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang   +1 more
wiley   +2 more sources

Léon Péan de Saint-Gilles

open access: yesEducación Química
Léon Péan de Saint-Gilles (1832-1863) was a French chemist, without a formal education,  who studied the allotropy of sulfur and the properties and reactions of the different species, the oxidizing properties of potassium permanganate, the oxidation of ...
Jaime Wisniak
doaj   +1 more source

In Situ Bioorthogonal Synthesis of PROTACs via Dual‐Responsive Cleavage for Synergistic Photo‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
A bioactive self‐delivering SNAP‐TAC platform responds to tumor‐associated cathepsin B and glutathione, enabling in situ bioorthogonal synthesis of a BRD4‐degrading proteolysis‐targeting chimera within the tumor microenvironment. The resulting BRD4 degradation and PD‐L1 downregulation synergize with photodynamic therapy‐induced immunogenic cell death ...
Shiqin Jian   +14 more
wiley   +1 more source

Screening of Food Grade Lipases to be Used in Esterification and Interesterification Reactions of Industrial Interest

open access: yes, 2010
Seven food grade commercially available lipases were immobilized by covalent binding on polysiloxane-polyvinyl alcohol (POS-PVA) hybrid composite and screened to mediate reactions of industrial interest.
PAULA, Ariela Veloso de   +4 more
core   +1 more source

Impact of Threading State on the Mechanics of γ‐Cyclodextrin–Pyrene Gels

open access: yesAngewandte Chemie, EarlyView.
Tuning the threading state of discrete γ‐cyclodextrin (γ‐CD)–pyrene pseudorotaxane crosslinkers controls gel topology and ring mobility. The resulting doubly threaded slide‐ring networks exhibit solvent‐switchable dissipative dynamics, high extensibility, rate‐dependent mechanics, and low hysteresis, revealing how crosslink topology governs macroscopic
Jongwon Oh   +8 more
wiley   +2 more sources

Targeted‐Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy

open access: yesAdvanced Science, EarlyView.
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing   +9 more
wiley   +1 more source

Estudos de reações de transesterificação com lipases imobilizadas e determinação de coeficiente de difusão de ésteres em organo-gel / [PDF]

open access: yes, 1999
Tese (Doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas.As lipases de Chromobacterium viscosum, Pseudomonas sp, Microbial e Lipolase, imobilizadas em organo-gel (MBG) de hexano foram usadas como ...
João, Jair Juarez
core  

Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont

open access: yesAngewandte Chemie, EarlyView.
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley   +11 more
wiley   +2 more sources

Computational and Data‐Driven Strategies for Lignocellulosic Biomass Valorization: From Multiscale Modeling to Digitalized Biorefinery Design

open access: yesAdvanced Science, EarlyView.
This Review critically connects structural recalcitrance, molecular modeling, solvent and catalyst design, pyrolysis, machine learning, reactor simulation, and FAIR digital infrastructure. Emphasis is placed on experimentally validated information transfer across scales, uncertainty and applicability domains, and the recycle, durability, techno ...
Abdullahi Bello Umar   +9 more
wiley   +1 more source

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