Results 41 to 50 of about 3,685 (173)

Accurate determination of node and arc multiplicities in de bruijn graphs using conditional random fields

open access: yesBMC Bioinformatics, 2020
Background De Bruijn graphs are key data structures for the analysis of next-generation sequencing data. They efficiently represent the overlap between reads and hence, also the underlying genome sequence.
Aranka Steyaert   +2 more
doaj   +1 more source

DRAGoM: Classification and Quantification of Noncoding RNA in Metagenomic Data

open access: yesFrontiers in Genetics, 2021
Noncoding RNAs (ncRNAs) play important regulatory and functional roles in microorganisms, such as regulation of gene expression, signaling, protein synthesis, and RNA processing. Hence, their classification and quantification are central tasks toward the
Ben Liu   +6 more
doaj   +1 more source

Bisecting de Bruijn and Kautz graphs

open access: yesDiscrete Applied Mathematics, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
José D. P. Rolim   +3 more
openaire   +1 more source

Identifying similar transcripts in a related organism from de Bruijn graphs of RNA-Seq data, with applications to the study of salt and waterlogging tolerance in Melilotus

open access: yesBMC Genomics, 2019
Background A popular strategy to study alternative splicing in non-model organisms starts from sequencing the entire transcriptome, then assembling the reads by using de novo transcriptome assembly algorithms to obtain predicted transcripts. A similarity
Shuhua Fu   +5 more
doaj   +1 more source

Practical dynamic de Bruijn graphs [PDF]

open access: yesBioinformatics, 2018
Abstract Motivation The de Bruijn graph is fundamental to the analysis of next generation sequencing data and so, as datasets of DNA reads grow rapidly, it becomes more important to represent de Bruijn graphs compactly while still supporting fast assembly. Previous implementations of compact de Bruijn
Victoria G. Crawford   +4 more
openaire   +3 more sources

BdBG: a bucket-based method for compressing genome sequencing data with dynamic de Bruijn graphs [PDF]

open access: yesPeerJ, 2018
Dramatic increases in data produced by next-generation sequencing (NGS) technologies demand data compression tools for saving storage space. However, effective and efficient data compression for genome sequencing data has remained an unresolved challenge
Rongjie Wang   +4 more
doaj   +2 more sources

Colouring of cycles in the de bruijn graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2000
The authors show that the problem of finding the family of all locally reducible factors in the binary de Bruijn graph of order \(k\) is equivalent to the problem of finding all colourings of the edges in the binary de Bruijn graph of order \(k-1\), where each vertex belongs to exactly two cycles of different colours.
Ewa Lazuka, Jerzy Zurawiecki
openaire   +2 more sources

Fully Dynamic de Bruijn Graphs [PDF]

open access: yes, 2016
We present a space- and time-efficient fully dynamic implementation de Bruijn graphs, which can also support fixed-length jumbled pattern matching.
Djamal Belazzougui   +3 more
openaire   +2 more sources

Succinct de Bruijn Graphs

open access: yes, 2012
We propose a new succinct de Bruijn graph representation. If the de Bruijn graph of k-mers in a DNA sequence of length N has m edges, it can be represented in 4m+o(m) bits. This is much smaller than existing ones. The numbers of outgoing and incoming edges of a node are computed in constant time, and the outgoing and incoming edge with given label are ...
Alexander Bowe   +3 more
openaire   +1 more source

Making de Bruijn Graphs Eulerian.

open access: yes, 2022
A directed multigraph is called Eulerian if it has a circuit which uses each edge exactly once. Euler’s theorem tells us that a weakly connected directed multigraph is Eulerian if and only if every node is balanced. Given a collection S of strings over an alphabet Σ, the de Bruijn graph (dBG) of order k of S is a directed multigraph G_{S,k}(V,E), where
G. Bernardini (Giulia)   +5 more
openaire   +6 more sources

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