Results 71 to 80 of about 3,685 (173)
BrownieAligner: accurate alignment of Illumina sequencing data to de Bruijn graphs
Background Aligning short reads to a reference genome is an important task in many genome analysis pipelines. This task is computationally more complex when the reference genome is provided in the form of a de Bruijn graph instead of a linear sequence ...
Mahdi Heydari +3 more
doaj +1 more source
ABSTRACT Binary search trees (BSTs) are fundamental data structures whose performance is largely governed by tree height. We introduce a block model for constructing BSTs by embedding internal BSTs into the nodes of an external BST—a structure motivated by parallel data architectures—corresponding to composite permutations formed via Kronecker or ...
John Peca‐Medlin, Chenyang Zhong
wiley +1 more source
Meta-colored Compacted de Bruijn Graphs
Abstract Motivation The colored compacted de Bruijn graph (c-dBG) has become a fundamental tool used across several areas of genomics and pangenomics. For example, it has been widely adopted by methods that perform read mapping or alignment, abundance estimation, and subsequent ...
Giulio Ermanno Pibiri +2 more
openaire +2 more sources
Simplitigs as an efficient and scalable representation of de Bruijn graphs
de Bruijn graphs play an essential role in bioinformatics, yet they lack a universal scalable representation. Here, we introduce simplitigs as a compact, efficient, and scalable representation, and ProphAsm, a fast algorithm for their computation.
Karel Břinda +2 more
doaj +1 more source
Using a sample of 978 Chinese adolescents, this graphical abstract presents a moderated mediation model in which sleep quality (SQ) partially mediates the negative effect of short video addiction (SVA) on executive function (EF), while physical activity (PA) moderates the direct SVAEF pathway.
Ting Xiao +7 more
wiley +1 more source
Bidirectional Variable-Order de Bruijn Graphs [PDF]
Compressed suffix trees and bidirectional FM-indexes can store a set of strings and support queries that let us explore the set of substrings they contain, adding and deleting characters on both the left and right, but they can use much more space than a de Bruijn graph for the strings.
Djamal Belazzougui +4 more
openaire +4 more sources
Background Identifying the locations of gene breakpoints between species of different taxonomic groups can provide useful insights into the underlying evolutionary processes.
Lisa Fiedler +3 more
doaj +1 more source
Wolf Presence Disrupts Seasonal Variation in Hair Cortisol Among Free‐Ranging Beef Cattle
Predators exert indirect effects on prey populations beyond direct predation, but how predator reintroduction restructures prey physiology remains poorly understood. Using hair cortisol analysis in cattle exposed versus unexposed to wolves, we found that wolf presence disrupted normal seasonal cortisol regulation patterns.
Christina M. Nord +6 more
wiley +1 more source
Comparing methods for constructing and representing human pangenome graphs
Background As a single reference genome cannot possibly represent all the variation present across human individuals, pangenome graphs have been introduced to incorporate population diversity within a wide range of genomic analyses.
Francesco Andreace +3 more
doaj +1 more source
Schematic illustration of the mechanism underlying the differences between SARA‐susceptible and SARA‐tolerant dairy goats fed a high‐concentrate diet. SARA‐susceptible goats (HCS) exhibit low rumen pH and metabolic decline, characterized by epithelial inflammation.
Jingyi Xu +10 more
wiley +1 more source

