Results 211 to 220 of about 563,940 (260)

De novo design of quasisymmetric two-component protein cages. [PDF]

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Wang S   +23 more
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De novo saccular aneurysms

Neurosurgery, 1988
ABSTRACT The authors report two patients with aneurysmal subarachnoid hemorrhage in whom carotid arteriography revealed aneurysms that had developed at previously normal locations and from infundibula during the years since initial angiography. Neither of these patients had congenital anomalies of the cerebral circulation and, apart from
B K, Misra   +3 more
openaire   +2 more sources

De novo metalloprotein design

Nature Reviews Chemistry, 2021
Natural metalloproteins perform many functions - ranging from sensing to electron transfer and catalysis - in which the position and property of each ligand and metal, is dictated by protein structure. De novo protein design aims to define an amino acid sequence that encodes a specific structure and function, providing a critical test of the ...
Matthew J. Chalkley   +2 more
openaire   +2 more sources

De novo design of biocatalysts

Current Opinion in Chemical Biology, 2002
The challenging field of de novo enzyme design is beginning to produce exciting results. The application of powerful computational methods to functional protein design has recently succeeded at engineering target activities. In addition, efforts in directed evolution continue to expand the transformations that can be accomplished by existing enzymes ...
Bolon, Daniel N.   +2 more
openaire   +3 more sources

De novo trisomy 16p

American Journal of Medical Genetics, 1997
We report on a patient with psychomotor retardation and a pattern of malformations comprising single umbilical artery, craniofacial anomalies, severe truncal hypotonia, and lower-limb hyporreflexia. G-banding cytogenetics demonstrated a 16p+ chromosome. Parental chromosomes were normal.
J L, Carrasco Juan   +4 more
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Becoming a de novo gene

Nature Ecology & Evolution, 2019
Analysis of genomes, transcriptomes and proteomes from recently diverged rice species provides mechanistic insight into the process of de novo gene origination.
Erich, Bornberg-Bauer, Brennen, Heames
openaire   +2 more sources

De novo and recurrent malignancy

Best Practice & Research Clinical Gastroenterology, 2020
Cancer is an important cause of morbidity and mortality after liver transplantation and can occur through three mechanisms: recurrence of a recipient's pre-transplant malignancy, donor-related transmission and de novo development. Currently, the decision to list a patient with a history of malignancy is an individual one.
Shalaby, Sarah, Burra, Patrizia
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De novo (11;13) translocation

Human Genetics, 1975
A male infant is described with unusual facial appearance, clubfeet, and moderate hydrocephalus internus without obvious deficiency in mental and physical development. Cytogenetic studies revealed a karyotype of 45,XY,--C,--D,+t(C;D). A chromosome 11 and a 13 are involved in the formation of the translocation chromosome.
Christa Fonatsch   +2 more
openaire   +2 more sources

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