Results 221 to 230 of about 563,940 (260)

De Novo Synthesis of (+)-Isofregenedol

The Journal of Organic Chemistry, 2008
An efficient enantioselective synthesis of (+)-isofregenedol was achieved in 13 steps from commercially available cyclohexene oxide without the use of protecting groups. The tetrahydronaphthalenic core of isofregenedol was obtained via a gold(I)-catalyzed benzannulation recently developed in our laboratory.
Maxime, Riou, Louis, Barriault
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De novo cerebral aneurysms

Voprosy neirokhirurgii imeni N.N. Burdenko, 2015
To substantiate the reasonability and duration of angiographic follow-up of patients operated on for cerebral aneurysms to rule out de novo aneurysm formation.The results of angiographic examination (cerebral angiography and SCT angiography) of 43 patients with cerebral aneurysms operated on at the Burdenko Neurosurgical Institute in 1995-2012 are ...
A S, Kheireddin, Yu M, Filatov, O B, Belousova, Sh Sh, Eliava, I A, Sazonov, A N, Kaftanov, S A, Maryashev   +6 more
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De Novo Synthesis of Monosaccharides

ChemInform, 2001
AbstractFor Abstract see ChemInform Abstract in Full Text.
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De Novo Design Methods

2003
The design of novel, pharmaceutically relevant compounds complementary to a given target binding site has long been considered as the “holy grail” in drug design.
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DNA Methylation de Novo

Science, 1999
One way in which the cell silences genes is to add methyl groups to cytosine (C) bases that are located next to guanine (G) bases in the DNA. The enzymes responsible for this are called the DNA methyltransferases (Dnmts). In a Perspective, Bird discusses several recent reports that identify two new Dnmts (Dnmt3a and 3b) and demonstrate that ...
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Novos modos de vigiar, novos modos de punir

2020
As autoras fazem reflexões conceituais, a partir da história real de algumas crianças, sobre as raízes dos processos de patologização e medicalização da vida e os modos pelos quais tais processos se articulam com preconceitos e intolerância com as diferenças, com o silenciamento de questionamentos e de utopias.
Moysés, Maria Aparecida Affonso, Collares, Cecília Azevedo Lima   +1 more
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De Novo Gene Birth

Molecular Biology
According to classic ideas, new genes emerge from old genes by duplication or horizontal transfer. Analyses of a large number of genomes in recent decades have shown that some genes have no visible homologs and have presumably emerged de novo from previously noncoding sequences.
E O, Aristova, I A, Volkhin, A A, Denisova, P A, Nikitin, E R, Petrukhin   +4 more
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Regulation of de novo methylation

1993
It has become dogma that vertebrate DNA, and indeed the DNA of most animals, contains methylcytosine that is restricted to the dinucleotide MG (where M is 5-methylcytosine). Plants have a higher proportion of DNA cytosines methylated largely because they have additional methylcytosine in the trinucleotide sequence MNG (Belanger and Hepburn, 1990).
R. L. Adams, H. Lindsay, REALE, Anna, C. Seivwright, S. Kass, M. Cummings, C. Houlston   +6 more
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De Novo Drug Design

2010
Computer-assisted molecular design supports drug discovery by suggesting novel chemotypes and compound modifications for lead structure optimization. While the aspect of synthetic feasibility of the automatically designed compounds has been neglected for a long time, we are currently witnessing an increased interest in this topic. Here, we review state-
Markus, Hartenfeller, Gisbert, Schneider
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Catalysis and Electron Transfer in De Novo Designed Metalloproteins

Chemical Reviews, 2022
Winston C Pitts, Vincent Pecoraro, Karl Koebke   +2 more
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