Results 21 to 30 of about 111,403 (262)
The sequence and de novo assembly of the wild yak genome [PDF]
Scientific Data, 2020 AbstractVulnerable populations of wild yak (Bos mutus), the wild ancestral species of domestic yak, survive in extremely cold, harsh and oxygen-poor regions of the Qinghai-Tibetan Plateau (QTP) and adjacent high-altitude regions. In this study, we sequenced and assembled its genomede novo.
Liu, Yanbin +7 more
openaire +3 more sources
G3: Genes, Genomes, Genetics, 2016 The availability of genomes across the tree of life is highly biased toward vertebrates, pathogens, human disease models, and organisms with relatively small and simple genomes.
Xiaofan Zhou +5 more
doaj +1 more source
Effects of GC bias in next-generation-sequencing data on de novo genome assembly. [PDF]
PLoS ONE, 2013 Next-generation-sequencing (NGS) has revolutionized the field of genome assembly because of its much higher data throughput and much lower cost compared with traditional Sanger sequencing. However, NGS poses new computational challenges to de novo genome
Yen-Chun Chen +4 more
doaj +1 more source
Survey of the Applications of NGS to Whole-Genome Sequencing and Expression Profiling [PDF]
Genomics & Informatics, 2012 Recently, the technologies of DNA sequence variation and gene expression profiling have been used widely as approaches in the expertise of genome biology and genetics.
Jong-Sung Lim +7 more
doaj +1 more source
Bandage: interactive visualisation of de novo genome assemblies [PDF]
Bioinformatics, 2015 Abstract Summary While de novo assembly graphs contain assembled contigs (nodes), the connections between those contigs (edges) are difficult for users to access. Bandage (a B ioinformatics
Ryan R. Wick +3 more
openaire +3 more sources
dnAQET: a framework to compute a consolidated metric for benchmarking quality of de novo assemblies
BMC Genomics, 2019 Background Accurate de novo genome assembly has become reality with the advancements in sequencing technology. With the ever-increasing number of de novo genome assembly tools, assessing the quality of assemblies has become of great importance in genome ...
Gokhan Yavas, Huixiao Hong, Wenming Xiao
doaj +1 more source
Genome-scale de novo assembly using ALGA [PDF]
Bioinformatics, 2021 Abstract Motivation There are very few methods for de novo genome assembly based on the overlap graph approach. It is considered as giving more exact results than the so-called de Bruijn graph approach but in much greater time and of much higher memory usage.
Sylwester Swat +7 more
openaire +2 more sources
Extreme-Scale De Novo Genome Assembly [PDF]
, 2017 De novo whole genome assembly reconstructs genomic sequence from short, overlapping, and potentially erroneous DNA segments and is one of the most important computations in modern genomics. This work presents HipMER, a high-quality end-to-end de novo assembler designed for extreme scale analysis, via efficient parallelization of the Meraculous code ...
Evangelos Georganas +6 more
openaire +2 more sources
Scalable De Novo Genome Assembly Using Pregel [PDF]
2018 IEEE 34th International Conference on Data Engineering (ICDE), 2018 De novo genome assembly is the process of stitching short DNA sequences to generate longer DNA sequences, without using any reference sequence for alignment. It enables high-throughput genome sequencing and thus accelerates the discovery of new genomes.
Da Yan 0001 +4 more
openaire +2 more sources
The sequence and de novo assembly of hog deer genome [PDF]
Scientific Data, 2019 AbstractHog deer (Axis porcinus) is a small deer species in family Cervidae and has been undergoing a serious and global decline during the past decades. Chengdu Zoo currently holds a captive population of hog deer with sufficient genetic diversity in China. We sequenced andde novoassembled its genome sequence in the present study.
Wang, Wei +18 more
openaire +2 more sources