De Novo Genome Assembly and Annotation of the Arunachali Yak. [PDF]
The Arunachali yak (Bos grunniens), a high-altitude ruminant endemic to India, is genetically and economically significant for pastoral communities. However, challenges such as population decline, inbreeding, and genetic dilution through crossbreeding threaten its conservation.
Pukhrambam M +13 more
europepmc +4 more sources
Short read Illumina data for the de novo assembly of a non-model snail species transcriptome (Radix balthica, Basommatophora, Pulmonata), and a comparison of assembler performance [PDF]
Background: Until recently, read lengths on the Solexa/Illumina system were too short to reliably assemble transcriptomes without a reference sequence, especially for non-model organisms.
Wheat, Christopher W. +10 more
core +2 more sources
The availability of genomes across the tree of life is highly biased toward vertebrates, pathogens, human disease models, and organisms with relatively small and simple genomes.
Xiaofan Zhou +5 more
doaj +1 more source
Effects of GC bias in next-generation-sequencing data on de novo genome assembly. [PDF]
Next-generation-sequencing (NGS) has revolutionized the field of genome assembly because of its much higher data throughput and much lower cost compared with traditional Sanger sequencing. However, NGS poses new computational challenges to de novo genome
Yen-Chun Chen +4 more
doaj +1 more source
An improved genome of the model marine alga Ostreococcus tauri unfolds by assessing Illumina de novo assemblies [PDF]
Background: Cost effective next generation sequencing technologies now enable the production of genomic datasets for many novel planktonic eukaryotes, representing an understudied reservoir of genetic diversity. O.
Moreau, Hervé +48 more
core +1 more source
Survey of the Applications of NGS to Whole-Genome Sequencing and Expression Profiling [PDF]
Recently, the technologies of DNA sequence variation and gene expression profiling have been used widely as approaches in the expertise of genome biology and genetics.
Jong-Sung Lim +7 more
doaj +1 more source
De novo assembly of a 40 Mb eukaryotic genome from short sequence reads: Sordaria macrospora, a model organism for fungal morphogenesis [PDF]
Filamentous fungi are of great importance in ecology, agriculture, medicine, and biotechnology. Thus, it is not surprising that genomes for more than 100 filamentous fungi have been sequenced, most of them by Sanger sequencing.
Kück Ulrich +61 more
core +2 more sources
Bandage: interactive visualisation of de novo genome assemblies [PDF]
Abstract Summary While de novo assembly graphs contain assembled contigs (nodes), the connections between those contigs (edges) are difficult for users to access. Bandage (a B ioinformatics
Ryan R. Wick +3 more
openaire +3 more sources
dnAQET: a framework to compute a consolidated metric for benchmarking quality of de novo assemblies
Background Accurate de novo genome assembly has become reality with the advancements in sequencing technology. With the ever-increasing number of de novo genome assembly tools, assessing the quality of assemblies has become of great importance in genome ...
Gokhan Yavas, Huixiao Hong, Wenming Xiao
doaj +1 more source
ling-lyang/Leptodactylus-fuscus-genome: de novo genome assembly of Leptodactylus fuscus
A de novo genome assembly of Leptodactylus ...
Lu "Ling" Yang
core +1 more source

