Results 121 to 130 of about 789,084 (305)

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Advanced Process Control for Clinker Rotary Kiln and Grate Cooler. [PDF]

Sensors (Basel), 2023
Zanoli SM, Pepe C, Astolfi G.
europepmc   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Improved terminal sliding mode control based on MPC for LIM applied to linear metro. [PDF]

Sci Rep
Hamad SA, El-Sousy FFM, Ismail MM, Elmorshedy MF, Almakhles D, Ghalib MA.   +5 more
europepmc   +1 more source

Multiresolution GPC-Structured Control of a Single-Loop Cold-Flow Chemical Looping Testbed. [PDF]

Energies (Basel), 2020
Zhang S, Bentsman J, Lou X, Neuschaefer C, Lee Y, El-Kebir H.   +5 more
europepmc   +1 more source

Parental Investment by Birth Fathers and Stepfathers : Roles of Mating Effort and Childhood Co-residence Duration. [PDF]

Hum Nat, 2023
Pettay JE, Danielsbacka M, Helle S, Perry G, Daly M, Tanskanen AO.   +5 more
europepmc   +1 more source

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

Advanced Science, EarlyView.
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin, Aini Pan, Zhuoning Miao, Yanyan Zhao, Xianan Mo, Heng Sun, Chunmei Fan, Junyu Guo, Bingbing Wu, Weiliang Shen, Qiangqiang Zheng, Jun Lu, Xi Jiang, Zi Yin, Xiao Chen   +14 more
wiley   +1 more source

Finite set model predictive control of permanent magnet synchronous motor current based on super twisting sliding mode observer. [PDF]

PLoS One
Ren H, Su C, Long R.
europepmc   +1 more source

Adaptive Traffic Signal Control: Game-Theoretic Decentralized vs. Centralized Perimeter Control. [PDF]

Sensors (Basel), 2021
Elouni M, Abdelghaffar HM, Rakha HA.
europepmc   +1 more source