Results 11 to 20 of about 51 (51)

Optimal timing to assess exercise‐induced oxidative stress: A systematic review and meta‐analysis

open access: yesExperimental Physiology, EarlyView.
Abstract There is a lack of consensus on optimal timing to assess redox biomarkers post‐exercise, limiting methodological standardisation and linking oxidative stress to physiology. We determined optimal post‐exercise oxidative stress assessment times using three redox biomarkers: glutathione, F2‐isoprostanes and protein carbonyls.
Chrysovalantis Stachteas   +12 more
wiley   +1 more source

Regional Volume of Atrial Fibrillation Catheter Ablation Is Not Associated With Increased Per Capita Medical Costs

open access: yesJournal of Arrhythmia, Volume 42, Issue 2, April 2026.
This ecological study of 47 Japanese prefectures demonstrates that regional medical costs are primarily driven by aging and chronic disease rather than atrial fibrillation catheter ablation, which was found to be a cost‐neutral intervention whose initial expenses are likely offset by the long‐term prevention of costly complications.
Takahiro Kamihara   +3 more
wiley   +1 more source

Percutaneous Versus Surgical Cannulation for Veno‐Arterial Extracorporeal Life Support: A Systematic Review and Meta‐Analysis

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Extracorporeal life support (ECLS) is a critical intervention in the management of severe cardiac and respiratory failure. Among the commonly used cannulation techniques, percutaneous cannulation (PC) and surgical cannulation (SC) are most prevalent; however, their comparative safety and effectiveness remain under debate ...
Syeda Zuha Sami   +7 more
wiley   +1 more source

Real‐Time Detection and Prevention of DoS Attack in Unmanned Marine Vehicles Using Machine Learning

open access: yesSECURITY AND PRIVACY, Volume 9, Issue 2, March/April 2026.
ABSTRACT Unmanned marine vehicles (UMVs) are one of the most crucial components of the underwater communication and surveillance system in the marine and oceanographic environment. This research introduces a novel approach to stabilize the connection in an unstable underwater environment by inheriting features of communication velocities.
Noman Ali   +8 more
wiley   +1 more source

Higher‐Level Structural Classification of Pseudomonas Cyclic Lipopeptides through Their Bioactive Conformation

open access: yesAdvanced Science, Volume 13, Issue 12, 27 February 2026.
Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács   +9 more
wiley   +1 more source

Substitution Kinetics, DNA/BSA Interactions, Cytotoxicity Evaluation and Computational Analysis of [bis‐(azaaryl)amine)Pt(II)/Pd(II)Cl] Complexes, Azaaryl = Quinoline or Phenanthridine

open access: yesBioinorganic Chemistry and Applications, Volume 2026, Issue 1, 2026.
The search for metal‐based anticancer agents with improved efficacy and reduced side effects is ongoing. The activities of these anticancer drugs depend on their aqueous stability, substitutional reactivity at target sites (cytotoxicity) and nontarget sites (toxicity), as well as their transportation and cell bioavailability.
Phakamani C. Dlamini   +8 more
wiley   +1 more source

Differential Phase Contrast Imaging to Predict MSC Immune Function

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 28, November 3, 2025.
This work employs quantitative differential phase contrast (qDPC) imaging technique to non‐invasively extract morphological features from live Mesenchymal Stromal Cells (MSCs) for single cell prediction on cell immunomodulatory capacity. This work establishes a foundation for scalable, non‐destructive monitoring of MSCs immunomodulatory capacity ...
Kejie Rui   +5 more
wiley   +1 more source

Brain Connectivity Gradients Alterations in Discordant Cerebrospinal Fluid Profile for Alzheimer's Disease Biomarkers

open access: yesHuman Brain Mapping, Volume 46, Issue 16, November 2025.
We compared individuals with concordant (A+T+) and discordant (A−T+) CSF profiles, the latter showing elevated phosphorylated tau without evidence of amyloid accumulation. Gradient analyzes of structural and functional connectivity revealed distinct patterns: default mode network involvement in A+T+ and occipito‐temporal cortex involvement in A−T ...
Lorenzo Pini   +9 more
wiley   +1 more source

A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
A hydrogel microneedle‐based system enables whole testicular cultivation, supporting spermatogonial proliferation and enhancing spermatogenesis in vitro. This ‘whole testicular spermatogonia pool’ (WTSP) significantly increases spermatid production and fertility potential in mice. This system also promotes spermatogonial expansion in human fetal testes,
Yu Xia   +14 more
wiley   +1 more source

SenExo‐cCCT2 Reprograms Senescence Response and Anti‐Tumor Immunity Following FOLFIRINOX Chemotherapy in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
This study demonstrates that SenExo‐cCCT2 enables targeted delivery of cCCT2 to pancreatic cancer cells, where it disrupts IPO13‐mediated nuclear translocation of UBC9, impairing SUMOylation‐dependent DNA damage repair and inducing senescence. Senescent tumor cells secrete CXCL10 to recruit CD8⁺ T‐cells while upregulating PD‐L1.
Shuncang Zhu   +18 more
wiley   +1 more source

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