Results 31 to 40 of about 247,945 (341)
OncoImmunology, 2018 Preclinical evidence suggests that high-dose hypofractionated ionizing radiation (IR) can enhance anti-tumor immunity and result in significant tumor control when combined with immune checkpoint blockade (ICB).
Megan Morisada +9 more
doaj +1 more source
Determining if T cell antigens are naturally processed and presented on HLA class I molecules
BMC Immunology, 2022 Background Determining T cell responses to naturally processed and presented antigens is a critical immune correlate to determine efficacy of an investigational immunotherapeutic in clinical trials.
Jay Friedman +5 more
doaj +1 more source
The nicotinic receptor of cochlear hair cells: A possible pharmacotherapeutic target? [PDF]
, 2009 Mechanosensory hair cells of the organ of Corti transmit information regarding sound to the central nervous system by way of peripheral afferent neurons.
Elgoyhen, Ana Belen +2 more
core +1 more source
Shedding light on optical cochlear implant progress
EMBO Molecular Medicine, 2020 Electrical cochlear implants (CI) currently lack the frequency and intensity resolution to allow detection of complex sounds in background noise. The use of microscale optoelectronics in conjunction with optogenetics provides a promising direction in CI ...
Siân R Kitcher, Catherine JC Weisz
doaj +1 more source
Deafness: Disability or Culture? Best Practices Regarding Controversial Interventions for Deaf and Hard of Hearing Students [PDF]
, 2020 Background: Many people in the deaf community view deafness as a distinct culture, with its own unique language and history. They reject the use of assistive technologies which can restore hearing for themselves and their children.
Ziemba, Jacob
core +1 more source
Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform [PDF]
, 2012 Background: Hereditary hearing loss (HL) can originate from mutations in one of many genes involved in the complex process of hearing. Identification of the genetic defects in patients is currently labor intensive and expensive.
Bekaert, Sofie +16 more
core +2 more sources
Early assessment of vestibular function after unilateral cochlear implant surgery [PDF]
, 2019 Introduction : Cochlear implantation (CI) has been reported to negatively effect on the vestibular function. The study of the vestibular function has variably been conducted by different types of diagnostic tools. The combined use of modern, rapidly
Barbara, M +6 more
core +1 more source
Advanced Biology, EarlyView.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
Scientific ReportsBlast wave exposure, a leading cause of hearing loss and balance dysfunction among military personnel, arises primarily from direct mechanical damage to the mechanosensory hair cells and supporting structures or indirectly through excessive oxidative ...
Dalian Ding +3 more
doaj +1 more source