Results 31 to 40 of about 141,941 (296)

Cottonseed‐Derived Reusable Bio‐Carbon Gel Ink for DIW Printing Soft Electronic Textiles

Advanced Materials, EarlyView.
A reusable carbon‐gel ink, incorporating cottonseed peptone as a natural mediator, enables cross‐linked ionic polymer networks for advanced conductivity, stability, and biocompatibility. Compatible with direct‐ink‐writing, it facilitates flexible electronics on polymeric and textile substrates for multifunctional applications, including motion sensing,
King Yan Chung, Di Tan, Ziyu He, Xiao Li, Jian Lu, Qingjun Yang, Xinlong Liu, Bingang Xu   +7 more
wiley   +1 more source

The Relative and Combined Effects of Noise Exposure and Aging on Auditory Peripheral Neural Deafferentation: A Narrative Review

Frontiers in Aging Neuroscience, 2022
Animal studies have shown that noise exposure and aging cause a reduction in the number of synapses between low and medium spontaneous rate auditory nerve fibers and inner hair cells before outer hair cell deterioration.
Adnan M. Shehabi, Adnan M. Shehabi, Garreth Prendergast, Christopher J. Plack, Christopher J. Plack   +4 more
doaj   +1 more source

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

Advanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang, Yuehui Xi, Qiaojun Fang, Sai Shi, Fei Wang, Fuyu Xian, Zhongyang Zhang, Yuxin Yang, Xishuo Jin, Xiaomin Wang, Chen Cao, Hailin Zhang, Nikita Gamper, Zhigang Xu, Haitao Shen, Ping Lv   +15 more
wiley   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

Advanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin Sam George, Anthony J. Ricci
wiley   +1 more source

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

Advanced Science, EarlyView.
Cochlear implantation is the primary treatment for deafness, restoring functional hearing in over a million people. Recently, gene therapy has enabled biological hearing restoration in a small number of patients with OTOF‐related mutations. This perspective evaluates both approaches, concluding that cochlear implants will remain the standard for most ...
Fan‐Gang Zeng, Jieyu Qi, Chen‐Chi Wu, Yilai Shu, Renjie Chai   +4 more
wiley   +1 more source

Cognitive skills and reading in adults with Usher syndrome type 2

Frontiers in Psychology, 2015
Objective: To investigate working memory, phonological skills, lexical skills, and reading comprehension in adults with Usher syndrome type 2 (USH2).Design: The participants performed tests of phonological processing, lexical access, working memory and ...
Cecilia eHenricson, Cecilia eHenricson, Cecilia eHenricson, Björn eLyxell, Björn eLyxell, Björn eLyxell, Björn eLidestam, Björn eLidestam, Björn eLidestam, Claes eMöller, Claes eMöller, Claes eMöller, Claes eMöller   +12 more
doaj   +1 more source

Current Developments and Challenges in the Field of Biohybrid Neural Interfaces—A Scoping Review

Advanced Electronic Materials, EarlyView.
This scoping review explores recent advancements and persistent challenges in biohybrid neural interfaces, which integrate living cells with electronic devices to improve neural communication and implant biocompatibility. The article highlights key innovations, methodological diversity, and translational barriers, providing a comprehensive synthesis ...
Yi‐Lin Yu, Jameel Muzaffar, Veronica Philips, Yun‐Ju Yang, Damiano Giuseppe Barone, George G. Malliaras, Manohar Bance   +6 more
wiley   +1 more source

Effects of multiple sclerosis on the audio-vestibular system: a systematic review

BMJ Open, 2022
Objective Systematically investigate the effects of multiple sclerosis (MS) on the audio-vestibular system.Methods Systematic review of literature investigating audio-vestibular conditions in persons with MS (PwMS) aged ≥18 years.
Evrim Gür, Ghada Binkhamis, Karolina Kluk   +2 more
doaj   +1 more source

Genetics of Deafness [PDF]

Genetics Research International, 2012
Hearing impairment is the most common sensorineural deficit worldwide. Deafness has a major genetic component, and understanding how genetic variation impacts hearing needs to be extensively studied. The importance of this work is reflected in the review by Lufkin: “the sense of hearing is one of the most crucial senses endowed to a living organism and
Edi Lúcia Sartorato, Karen Friderici, Ignacio Del Castillo   +2 more
openaire   +3 more sources

Engineered RNA Devices for In Vivo Targeted Therapeutics via Advanced Delivery Systems

Aggregate, EarlyView.
Schematic illustration of engineered RNA devices for in vivo targeted therapeutics via advanced delivery systems. ABSTRACT Engineered RNA devices can identify disease‐specific markers and precisely regulate gene expression, which is of great significance to the development of precision medicine.
Wei Luo, Xia Liu, Ying Han, Yijing Duan, Chuao Yu, Na Kong, Tian Xie   +6 more
wiley   +1 more source