Results 71 to 80 of about 247,945 (341)
Cerebral Small Vessel Disease in Older Adults With Olfactory Dysfunction
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Poor vascular health has been associated with age‐related declines in sensory functions, including olfaction. The current study was designed to test the hypothesis that cerebral small vessel disease underlies poor olfactory function due to structural declines in brain regions that support olfaction.
Mark A. Eckert +3 more
wiley +1 more source
Frontiers in Molecular Neuroscience, 2019 The stria vascularis (SV) generates the endocochlear potential (EP) in the inner ear and is necessary for proper hair cell mechanotransduction and hearing.
Soumya Korrapati +10 more
doaj +1 more source
Genetic Hearing Loss Associated With Autoinflammation
Frontiers in Neurology, 2020 Sensorineural hearing loss can result from dysfunction of the inner ear, auditory nerve, or auditory pathways in the central nervous system. Sensorineural hearing loss can be associated with age, exposure to ototoxic drugs or noise, or mutations in ...
Hiroshi Nakanishi +10 more
doaj +1 more source
Studies of intercellular Ca2+ signaling and gap-junction coupling in the developing cochlea of mouse models affected by congenital hearing loss [PDF]
, 2013 Connexin 26 (Cx26) and connexin 30 (Cx30) form gap junction channels that allow the intercellular diffusion of the Ca2+ mobilizing second messenger IP3.
Rodriguez Hernandez, Laura
core +1 more source
Genetics Research International, 2012 Hearing impairment is the most common sensorineural deficit worldwide. Deafness has a major genetic component, and understanding how genetic variation impacts hearing needs to be extensively studied. The importance of this work is reflected in the review by Lufkin: “the sense of hearing is one of the most crucial senses endowed to a living organism and
Edi Lúcia Sartorato +2 more
openaire +3 more sources
Annals of Neurology, EarlyView.Objective Landau–Kleffner syndrome (LKS), is a rare, poorly‐understood epileptic encephalopathy with spike–wave activation in sleep associated with mutations in GRIN2A, encoding the N‐Methyl‐D‐Aspartate receptor (NMDAR) GluN2A subunit. Physicians rely on empirical treatments, with scarce information on treatment efficacy and outcomes.
Adeline Ngoh +15 more
wiley +1 more source
Neoplasia: An International Journal for Oncology Research, 2014 Cancer stem cells (CSC) and genes have been linked to cancer development and therapeutic resistance, but the signaling mechanisms regulating CSC genes and phenotype are incompletely understood. CK2 has emerged as a key signal serine/threonine kinase that
Hai Lu +7 more
doaj +1 more source
More than a Match: The Role of Football in Britain’s Deaf Community [PDF]
, 2001 The University of Central Lancashire has undertaken a major research project into the role of football within the deaf community in Britain. As well as reconstructing the long history of deaf involvement in football for the first time, the project has ...
Atherton, Martin +2 more
core +1 more source
Advanced NanoBiomed Research, EarlyView.Physical stimulation strategies have emerged as a therapeutic avenue for the regeneration of spiral ganglion neurons. This review explores diverse physical stimulation modalities—including topographical modulation, electrical stimulation, and photostimulation—each operating through distinct mechanisms to regulate SGN biological behavior. By elucidating
Yuhan Bai +7 more
wiley +1 more source
Heritability and complex segregation analysis of deafness in Jack Russell Terriers
BMC Veterinary Research, 2007 Background The association between patterns of pigmentation and deafness in the dog has a long-documented history, with reports dating back over one hundred years.
Strain George M +2 more
doaj +1 more source