Results 1 to 10 of about 9,743,642 (412)
In nematodes, environmental or physiological perturbations alter death's scaling of time. In human cancer, genetic perturbations alter death's curvature of time. Those changes in scale and curvature follow the constraining contours of death's invariant geometry.
arxiv +8 more sources
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent in Western countries, evolving into metabolic dysfunction-associated steatohepatitis (MASH) with a sexual dimorphism. Fertile women exhibit lower MASLD risk than men,
Carlos Cuño-Gómiz+7 more
doaj +1 more source
Immunogenic cell death (ICD) is a functionally unique form of cell death that promotes a T-cell-dependent anti-tumor immune response specific to antigens originating from dying cancer cells.
Dmitri V. Krysko+5 more
doaj +1 more source
Prostate apoptosis response-4 and tumor suppression: it’s not just about apoptosis anymore
The tumor suppressor prostate apoptosis response-4 (Par-4) has recently turned ‘twenty-five’. Beyond its indisputable role as an apoptosis inducer, an increasing and sometimes bewildering, new roles for Par-4 are being reported.
Anees Rahman Cheratta+5 more
doaj +1 more source
Non Coding RNAs as Regulators of Wnt/β-Catenin and Hippo Pathways in Arrhythmogenic Cardiomyopathy
Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy histologically characterized by the replacement of myocardium by fibrofatty infiltration, cardiomyocyte loss, and inflammation.
Marina Piquer-Gil+5 more
doaj +1 more source
Sorafenib and regorafenib, multikinase inhibitors (MKIs) used as standard chemotherapeutic agents for hepatocellular carcinoma (HCC), generate reactive oxygen species (ROS) during cancer treatment.
Blanca Cucarull+7 more
doaj +1 more source
In cancer cells only, TLR3 acquires death receptor properties by efficiently triggering the extrinsic pathway of apoptosis with Caspase-8 as apical protease.
Marie-Anaïs Locquet+6 more
doaj +1 more source
Counting statistics based on the analytic solutions of the differential-difference equation for birth-death processes [PDF]
Birth-death processes take place ubiquitously throughout the universe. In general, birth and death rates depend on the system size (corresponding to the number of products or customers undergoing the birth-death process) and thus vary every time birth or death occurs, which makes fluctuations in the rates inevitable.
arxiv +1 more source
Establishing riverine nutrient criteria using individual taxa thresholds [PDF]
Nutrient enrichment is one of the most pervasive impacts on aquatic ecosystems globally. Approaches to establish nutrient criteria that safeguard aquatic ecosystem health are highly variable and, in many instances, criteria are derived from correlations ...
Canning, A.D., Death, R.G.
core +1 more source
The ongoing crises of child sexual abuse by Christian institutions leaders across the Anglophone world continue to attract public attention and public inquiries.
Jodi Death
doaj +1 more source