Results 1 to 10 of about 9,743,642 (412)

Invariant death [PDF]

open access: yesF1000Research, 2016
In nematodes, environmental or physiological perturbations alter death's scaling of time. In human cancer, genetic perturbations alter death's curvature of time. Those changes in scale and curvature follow the constraining contours of death's invariant geometry.
arxiv   +8 more sources

Sex-based differences in natural killer T cell-mediated protection against diet-induced steatohepatitis in Balb/c mice

open access: yesBiology of Sex Differences, 2023
Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent in Western countries, evolving into metabolic dysfunction-associated steatohepatitis (MASH) with a sexual dimorphism. Fertile women exhibit lower MASLD risk than men,
Carlos Cuño-Gómiz   +7 more
doaj   +1 more source

In Vitro Veritas: From 2D Cultures to Organ-on-a-Chip Models to Study Immunogenic Cell Death in the Tumor Microenvironment

open access: yesCells, 2022
Immunogenic cell death (ICD) is a functionally unique form of cell death that promotes a T-cell-dependent anti-tumor immune response specific to antigens originating from dying cancer cells.
Dmitri V. Krysko   +5 more
doaj   +1 more source

Prostate apoptosis response-4 and tumor suppression: it’s not just about apoptosis anymore

open access: yesCell Death and Disease, 2021
The tumor suppressor prostate apoptosis response-4 (Par-4) has recently turned ‘twenty-five’. Beyond its indisputable role as an apoptosis inducer, an increasing and sometimes bewildering, new roles for Par-4 are being reported.
Anees Rahman Cheratta   +5 more
doaj   +1 more source

Non Coding RNAs as Regulators of Wnt/β-Catenin and Hippo Pathways in Arrhythmogenic Cardiomyopathy

open access: yesBiomedicines, 2022
Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy histologically characterized by the replacement of myocardium by fibrofatty infiltration, cardiomyocyte loss, and inflammation.
Marina Piquer-Gil   +5 more
doaj   +1 more source

Antioxidants Threaten Multikinase Inhibitor Efficacy against Liver Cancer by Blocking Mitochondrial Reactive Oxygen Species

open access: yesAntioxidants, 2021
Sorafenib and regorafenib, multikinase inhibitors (MKIs) used as standard chemotherapeutic agents for hepatocellular carcinoma (HCC), generate reactive oxygen species (ROS) during cancer treatment.
Blanca Cucarull   +7 more
doaj   +1 more source

Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma

open access: yesScientific Reports, 2021
In cancer cells only, TLR3 acquires death receptor properties by efficiently triggering the extrinsic pathway of apoptosis with Caspase-8 as apical protease.
Marie-Anaïs Locquet   +6 more
doaj   +1 more source

Counting statistics based on the analytic solutions of the differential-difference equation for birth-death processes [PDF]

open access: yes, 2023
Birth-death processes take place ubiquitously throughout the universe. In general, birth and death rates depend on the system size (corresponding to the number of products or customers undergoing the birth-death process) and thus vary every time birth or death occurs, which makes fluctuations in the rates inevitable.
arxiv   +1 more source

Establishing riverine nutrient criteria using individual taxa thresholds [PDF]

open access: yes, 2023
Nutrient enrichment is one of the most pervasive impacts on aquatic ecosystems globally. Approaches to establish nutrient criteria that safeguard aquatic ecosystem health are highly variable and, in many instances, criteria are derived from correlations ...
Canning, A.D., Death, R.G.
core   +1 more source

Identity, Forgiveness and Power in the Management of Child Sexual Abuse by Personnel in Christian Institutions

open access: yesInternational Journal for Crime, Justice and Social Democracy, 2013
The ongoing crises of child sexual abuse by Christian institutions leaders across the Anglophone world continue to attract public attention and public inquiries.
Jodi Death
doaj   +1 more source

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