Results 101 to 110 of about 259,494 (346)

PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo, Sinuo Chen, Jialei Sun, Ruchen Xu, Zhuoran Qi, Jie Li, Lianer Zhou, Yuan Fang, Tianshu Liu, Jinglin Xia   +9 more
wiley   +1 more source

IAM at CLEF eHealth 2018: Concept Annotation and Coding in French Death Certificates [PDF]

arXiv, 2018
In this paper, we describe the approach and results for our participation in the task 1 (multilingual information extraction) of the CLEF eHealth 2018 challenge. We addressed the task of automatically assigning ICD-10 codes to French death certificates. We used a dictionary-based approach using materials provided by the task organizers.
arxiv  

Amplifying Anti‐Tumor Immune Responses via Mitochondria‐Targeting Near‐Infrared Photodynamic Therapy

Advanced Science, EarlyView.
Interfacial Nd3+‐triplet energy transfer enables direct activation of molecular triplets under near‐infrared (NIR) irradiation for reactive oxygen species (ROS) generation. Photodynamic therapy (PDT) exaggerates hypoxia, which initiates subsequent hypoxia‐activated chemotherapy.
Cheng‐Ao Li, Junjie Nan, Qingxuan Ye, Bingzhu Zheng, Xiaomeng Dai, Jingya Li, Feng Wang, Huimin Ma, Yu Cheng, Jian Ruan, Weijia Fang, Peng Zhao, Renren Deng, Dong Cen   +13 more
wiley   +1 more source

Factors associated with the goal of treatment in the last week of life in old compared to very old patients: a population-based death certificate survey [PDF]

, 2014
Background: Little is known about the type of care older people of different ages receive at the end of life. The goal of treatment is an important parameter of the quality of end-of-life care. This study aims to provide an evaluation of the main goal of
Cohen, Joachim, Deliens, Luc, Smets, Tinne, Van Den Noortgate, Nele, Verhofstede, Rebecca   +4 more
core   +4 more sources

Cause of death in patients with end‐stage renal disease: assessing concordance of death certificates with registry reports

Australian and New Zealand Journal of Public Health, 2003
Objectives:To assess concordance in reporting, in two Australian national datasets, of cause of death of patients with end‐stage renal disease (ESRD). Methods:For deaths in 1997–99, we compared ‘cause of death’ and ‘primary renal disease’, as coded in ...
Shu Qin Li, Alan Cass, Joan Cunningham
doaj   +1 more source

Genetically Predicted 1400 Blood Metabolites in Relation to Risk of Prostate Cancer: A Mendelian Randomization Study

AGING MEDICINE, EarlyView.
This study employed Mendelian Randomization to assess 1,400 blood metabolites and found a significant inverse association between the glycine‐to‐serine ratio and prostate cancer risk, suggesting a potential causal relationship. ABSTRACT Objectives Metabolic dysregulation is common in cancer, yet evidence linking circulating metabolites to causal ...
Xiaojin Lu, Yongming Chen, Yuxiao Jiang, Jiaxin Ning, Shengjie Liu, Zhengtong Lv, Miao Wang, Huiming Hou, Ming Liu   +8 more
wiley   +1 more source

Initial Metabolic Profiles Are Associated with 7-Day Survival among Infants Born at 22-25 Weeks of Gestation. [PDF]

, 2018
OBJECTIVE:To evaluate the association between early metabolic profiles combined with infant characteristics and survival past 7 days of age in infants born at 22-25 weeks of gestation. STUDY DESIGN:This nested case-control consisted of 465 singleton live
Anderson, James G, Baer, Rebecca J, Jelliffe-Pawlowski, Laura L, Oltman, Scott P, Pantell, Matthew S, Partridge, J Colin, Rand, Larry, Rogers, Elizabeth E, Ryckman, Kelli K, Steurer, Martina A   +9 more
core   +1 more source

Inadequacies of death certification in Beirut: who is responsible?

Bulletin of the World Health Organization, 2002
OBJECTIVE: To assess the completeness of data on death certificates over the past 25 years in Beirut, Lebanon, and to examine factors associated with the absence of certifiers' signatures and the non-reporting of the underlying cause of death. METHODS: A
Sibai Abla M., Nuwayhid Iman, Beydoun May, Chaaya Monique   +3 more
doaj  

Accuracy of Death Certificates and Assessment of Factors for Misclassification of Underlying Cause of Death

Journal of Epidemiology, 2016
Background: Cause of death (COD) information taken from death certificates is often inaccurate and incomplete. However, the accuracy of Underlying CODs (UCODs) recorded on death certificates has not been comprehensively described when multiple diseases ...
Makiko Naka Mieno
doaj   +1 more source

External Validation of an Automated Surgical Step Recognition Model for Robotic Distal Gastrectomy (RDG) Using a Multicenter Dataset

Annals of Gastroenterological Surgery, EarlyView.
Our present study reveals that surgical step recognition performs moderately well when trained on video data from a single institution and applied to an external institution's data. Nevertheless, our model substantially improves its prediction capabilities when trained on the same amount of data from multiple institutions.
James S. Strong, Masahiro Yura, Masashi Takeuchi, Hirofumi Kawakubo, Tasuku Furube, Yusuke Maeda, Satoru Matsuda, Takahiro Kinoshita, Yuko Kitagawa   +8 more
wiley   +1 more source