Results 81 to 90 of about 2,688,047 (379)

Causes of mortality for Indonesian Hajj Pilgrims: comparison between routine death certificate and verbal autopsy findings. [PDF]

PLoS ONE, 2013
BACKGROUND: Indonesia provides the largest single source of pilgrims for the Hajj (10%). In the last two decades, mortality rates for Indonesian pilgrims ranged between 200-380 deaths per 100,000 pilgrims over the 10-week Hajj period.
Masdalina Pane, Sholah Imari, Qomariah Alwi, I Nyoman Kandun, Alex R Cook, Gina Samaan   +5 more
doaj   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Accuracy of death certification [PDF]

British Journal of Psychiatry, 2011
The death certificate allows underlying conditions leading to the cause of death, as well as other significant conditions unrelated to the immediate cause of death, to be listed. Perusal of statistics of the causes of death is instructive. The list of drugs in the Office for National Statistics’
openaire   +3 more sources

Patterns of risk of cancer in patients with metal-on-metal hip replacements versus other bearing surface types: a record linkage study between a prospective joint registry and general practice electronic health records in England. [PDF]

, 2013
BACKGROUND: There are concerns that metal-on-metal hip implants may cause cancer. The objective of this study was to evaluate patterns and timing of risk of cancer in patients with metal-on-metal total hip replacements (THR).
de Vries, Frank, Lalmohamed, Arief, Leufkens, Hubertus G M, MacGregor, Alexander J, Van Staa, Tjeerd, van Staa, Tjeerd P   +5 more
core   +2 more sources

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Evidence-based planning and costing palliative care services for children : novel multi-method epidemiological and economic exemplar [PDF]

, 2013
Background: Children’s palliative care is a relatively new clinical specialty. Its nature is multi-dimensional and its delivery necessarily multi-professional.
A Craft, Audit Scotland, C Feudtner, C Knapp, Ciarán Humphreys, D Bainbridge, Department of Health, Department of Health Western Australia, F Finlay, Gareth R Davies, J Noyes, J Noyes, Jane Noyes, K Lowson, K McNamara-Goodger, L Brook, L Fraser, Llinos Haf Spencer, Lucie Hobson, M Doug, Mary Devins, Mary Lewis, NPC, Public Health Wales, R Hain, R Hain, R Hain, R Hain, Rhiannon Tudor Edwards, Richard Hain, Richard P Hastings, Scottish Children and Young People's Palliative Care Executive Group (SCYPPEx), T Hughes-Hallet, Together for Short Lives, V Sugar, Vasiliki Totsika, Virginia Bennett, World Health Organisation   +37 more
core   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Socioeconomic status as a risk factor for dementia death:individual participant meta-analysis of 86 508 men and women from the UK [PDF]

, 2013
Background Life-course socioeconomic factors may have a role in dementia aetiology but there is a current paucity of studies. Meta-analyses of individual participant data would considerably strengthen this evidence base.
Cox, Emmanuel Stamatakis, Ferri, G. David Batty, John M. Starr, Mark Hamer, Marmot, Mika Kivimäki, MRC, Norton, Snowdon, Tom C. Russ, von Elm   +12 more
core   +1 more source

Associations of Stroke With Risk of Epilepsy: Results From the Atherosclerosis Risk in Communities (ARIC) Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To estimate the risk of epilepsy associated with stroke in a community‐based cohort, with consideration of stroke type, number, and severity. Methods Data from 15,100 Atherosclerosis Risk in Communities (ARIC) Study participants without stroke at baseline (1987–1989) were analyzed through 12/31/2022.
Jiping Zhou, Asma A. Ladak, Connor A. Law, Michelle C. Johansen, Anny Reyes, Silvia Koton, Sean Kelly, Jeubin Huang, Kamakshi Lakshminarayan, Rebecca F. Gottesman, Emily Johnson, Andrea L. C. Schneider   +11 more
wiley   +1 more source

Inadequacies of death certification in Beirut: who is responsible?

Bulletin of the World Health Organization
OBJECTIVE: To assess the completeness of data on death certificates over the past 25 years in Beirut, Lebanon, and to examine factors associated with the absence of certifiers' signatures and the non-reporting of the underlying cause of death. METHODS: A
Abla M. Sibai, Iman Nuwayhid, May Beydoun, Monique Chaaya   +3 more
doaj   +1 more source