Results 231 to 240 of about 3,285,539 (279)

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Apoptosis Modulation by LL-37: From Mitochondrial Cell Death to Prosurvival Signaling. [PDF]

Int J Mol Sci
Voronko OE, Novikova VS, Klychkova OO, Markina MP, Lee AA, Kashirskikh DA, Khotina VA, Gasanov VAO.   +7 more
europepmc   +1 more source

Pathophysiological mechanisms of cell death affecting graft survival in liver transplantation. [PDF]

World J Transplant
Mouratidou C, Pavlidis ET, Katsanos G, Kofinas A, Marneri AG, Stavrati KE, Tsoulfas G, Pavlidis TE.   +7 more
europepmc   +1 more source

Neurotoxicity of Synthetic Cannabinoid Receptor Agonist Cumyl-PINACA: An In Vitro Study on Rat Cortical Neurons and Astrocytes. [PDF]

Pharmaceuticals (Basel)
Jurič DM, Bulc Rozman K, Lipnik-Štangelj M, Šuput D, Brvar M.   +4 more
europepmc   +1 more source

Effect of Adenosine on the Morphological and Functional Integrity of Isolated Human Islets Exposed to Normoxic and Hypoxic Conditions. [PDF]

Bioengineering (Basel)
Brandhorst H, Brandhorst D, Spiers R, Acreman S, Christopherson L, Cornu A, Portnojs A, Al-Hasani K, Johnson PRV.   +8 more
europepmc   +1 more source

Apoptosis induced by death receptors.

Pharmaceutica Acta Helvetiae, 2000
Death receptors belong to the TNF receptor family and are characterised by an intracellular death domain that serves to recruit adapter proteins such as TRADD and FADD and cysteine proteases such as Caspase-8. Activation of Caspase-8 on the aggregated receptor leads to apoptosis. Triggering of death receptors is mediated through the binding of specific
Pascal Schneider, J Tschopp
exaly   +6 more sources

Death Receptors: Signaling and Modulation

Science, 1998
REVIEW Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors, on their surface.
Vishva Dixit, Avi Ashkenazi
exaly   +4 more sources

An introduction to death receptors in apoptosis

International Journal of Surgery, 2005
Apoptosis is a source of much research interest across many fields, including developmental biology, immunology and oncology. As the exact pathways of this process are identified, so too are potential avenues for therapeutic application. Death receptors are important in inducing apoptosis and together with their ligands have become a source of ...
A N Warrens
exaly   +3 more sources

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The Death Receptors

1999
In recent years apoptosis, also called programmed cell death, has been recognized to be the physiological way for a nucleated animal cell to die. Apoptosis takes care of unwanted, injured or virus-infected cells (Farber 1994; Collins 1995). Autoreactive T and B cells that are produced by the immune system by the millions every day are also eliminated ...
Peter, M. E., Scaffidi, C., Medema, J. P., Kischkel, F., Krammer, P. H.   +4 more
openaire   +4 more sources

Death Receptors and Apoptosis

Dermatologic Clinics, 2007
Interactions between death receptors from the tumor necrosis factor superfamily and their ligands play a crucial role in the development and the integrity of the epidermis. The major consequence resulting from death receptor targeting is apoptosis.
Contassot E, Gaide O, French LE
openaire   +3 more sources