Results 1 to 10 of about 479,268 (266)

Developing TRAIL/TRAIL death receptor-based cancer therapies

open access: yesCancer and Metastasis Reviews, 2018
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to its associated death receptors DR4 and DR5.
Qian Chu, Kongming Wu, Yuan Xun
exaly   +2 more sources

The significance of Fas, tumor necrosis factor-related apoptosis-inducing ligand and fibrinolytic factors in the assessment of malignant pleural effusion [PDF]

open access: yesArchives of Biological Sciences, 2022
Few studies have examined the usefulness of soluble apoptotic markers for the screening of pleural effusion. This study aimed to investigate the significance of Fas, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and fibrinolytic factors
Choi Jong Weon   +2 more
doaj   +1 more source

The Role of TRAIL in Apoptosis and Immunosurveillance in Cancer

open access: yesCancers, 2023
Simple Summary Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) plays an important role in apoptosis and tumor immunosurveillance. Because TRAIL selectively induces apoptosis in tumor cells, there is growing interest in using it as a
Julio M. Pimentel   +2 more
semanticscholar   +1 more source

Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes

open access: yesNature, 2021
Astrocytes are glial cells that are abundant in the central nervous system (CNS) and that have important homeostatic and disease-promoting functions1.
L. Sanmarco   +17 more
semanticscholar   +1 more source

Harnessing TRAIL-induced cell death for cancer therapy: a long walk with thrilling discoveries

open access: yesCell Death and Differentiation, 2022
Tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) can induce apoptosis in a wide variety of cancer cells, both in vitro and in vivo, importantly without killing any essential normal cells.
A. Montinaro, H. Walczak
semanticscholar   +1 more source

Multiple nest entrances alter foraging and information transfer in ants [PDF]

open access: yesRoyal Society Open Science, 2020
The ecological success of ants relies on their ability to discover and collectively exploit available resources. In this process, the nest entrances are key locations at which foragers transfer food and information about the surrounding environment.
Marine Lehue   +2 more
doaj   +1 more source

The TRAIL in the Treatment of Human Cancer: An Update on Clinical Trials

open access: yesFrontiers in Molecular Biosciences, 2021
TRAIL (tumor-necrosis factor related apoptosis-inducing ligand, CD253) and its death receptors TRAIL-R1 and TRAIL-R2 selectively trigger the apoptotic cell death in tumor cells.
M. Snajdauf   +7 more
semanticscholar   +1 more source

Near-Infrared Laser-Based Spatially Targeted Nano-enhanced Optical Delivery of Therapeutic Genes to Degenerated Retina

open access: yesMolecular Therapy: Methods & Clinical Development, 2020
Non-viral delivery of therapeutic genes into targeted areas of retina is essential for re-functionalizing the retinal circuitry. While a focused ultrafast laser beam has been recently used for intra-ocular delivery of molecules, it poses the significant ...
Subrata Batabyal   +5 more
doaj   +1 more source

Open trails in digraphs [PDF]

open access: yesOpuscula Mathematica, 2011
It has been shown in [S. Cichacz, A. Görlich, Decomposition of complete bipartite graphs into open trails, Preprint MD 022, (2006)] that any bipartite graph \(K_{a,b}\), is decomposable into open trails of prescribed even lengths.
Sylwia Cichacz, Agnieszka Görlich
doaj   +1 more source

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL

open access: yesEMBO Journal, 1997
Henning Walczak   +2 more
exaly   +2 more sources

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