Results 11 to 20 of about 395,211 (318)
Trailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer Cells [PDF]
Frontiers in Oncology, 2015 Resistance to chemotherapeutic drugs is the major hindrance in the successful cancer therapy. The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor (TNF) family of ligands, which initiates apoptosis in cancer cells through interaction with the death receptors DR4 and DR5.
Trivedi, Rachana, Mishra, Durga Prasad
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Journal of Clinical Investigation, 2003 Antigen-specific lymphocytes are involved in synovial proliferation within inflamed joints. Activated lymphocytes and synoviocytes from patients with rheumatoid arthritis express receptors that can bind TNF-related apoptosis-inducing ligand (TRAIL). A new study demonstrates that DCs pulsed with collagen and transduced with an adenovirus-based vector ...
George C, Tsokos, Maria, Tsokos
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Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer. [PDF]
, 2012 Thus, we evaluated the immunofluorescence pattern of TRAIL-receptors and E-cadherin to assess the fraction of membrane-bound TRAIL-receptors in 231 selected patients with early-stage CRC undergoing surgical treatment only.
Göke, Burkhard +32 more
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Cells, 2020 Human embryonic carcinoma (EC; NCCIT) cells have self-renewal ability and pluripotency. Cancer stem cell markers are highly expressed in NCCIT cells, imparting them with the pluripotent nature to differentiate into other cancer types, including breast ...
Nipin Sp +10 more
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On the Trail of Microparticles [PDF]
Circulation Research, 2009 Stimulation of a variety of cell types leads to the release of submicron vesicles that bud off from the plasma membrane. These so-called microparticles (MPs) or microvesicles are defined by their small size (0.1 to 1 μm) and the presence of surface antigens from the parental cells.1,2 MPs contribute to a variety of physiological and pathological ...
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Pioglitazone inhibits growth of carcinoid cells and promotes TRAIL-induced apoptosis by induction of p21(waf1/cip1) [PDF]
, 2001 Background/Aims: We investigated the effect of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonist pioglitazone on growth and TRAIL-induced apoptosis in carcinoid cells.
Göke, Burkhard +4 more
core +1 more source
Mondes du Tourisme, 2015 At St Pierre de Chartreuse (Isère), Common elected officials, community common Chartreuse Guiers and Chartreuse Regional Natural Park wanted to engage in tourism diversification to develop a "four-season tourism." Meanwhile, two companies specialized in ...
Clémence Perrin-Malterre
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Drug Delivery, 2017 Active targeting nanoparticles were developed to simultaneously codeliver tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Curcumin (Cur).
Xi Yang +5 more
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A Concept of a Cultural Tourist Route Following the Footsteps of Witold Gombrowicz in Buenos Aires [PDF]
Studia Periegetica, 2018 Buenos Aires is one of the most frequently chosen tourist destinations among the cities of Latin America. Apart from the generally known tourist attractions, it also offers activities for tourists with special interests.
Michał Faryś, Jolanta Kijowska
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Volatile oil of Teucrium alopecurus sensitizes colon cancer cells to TRAIL-induced cell death
Frontiers in Bioscience-Scholar, 2021 TNF-related apoptosis-inducing ligand (TRAIL/Apo2L), a member of cytokine family, is known to selectively induce apoptosis in cancer cells. However, developing resistance to TRAIL is a major obstacle in cancer therapy.
Fatma Guesmi +7 more
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