Results 31 to 40 of about 3,743,917 (243)
Characterisation of bovine leukocyte Ig-like receptors [PDF]
, 2012 Leukocyte Immunoglobulin-like receptors (LILR) are innate immune receptors involved in regulating both innate and adaptive immune functions. LILR show more interspecies conservation than the closely related Killer Ig-like receptors, and homologues have ...
Jones, DC +8 more
core +4 more sources
Combination of TRAIL with bortezomib shifted apoptotic signaling from DR4 to DR5 death receptor by selective internalization and degradation of DR4. [PDF]
PLoS ONE, 2014 TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) mediates apoptosis in cancer cells through death receptors DR4 and DR5 preferring often one receptor over another in the cells expressing both receptors.
Maxim L Bychkov +3 more
doaj +1 more source
Identification of an antiapoptotic protein complex at death receptors
, 2008 Stimulation of death receptors activates the extrinsic apoptotic signaling pathway that leads to cell death. Although many steps of this apoptotic signaling cascade are known, few mechanisms that counterbalance the death signal have been described.
Jope, Rs +9 more
core +1 more source
Toxins, 2014 Our previous findings have demonstrated that bee venom (BV) has anti-cancer activity in several cancer cells. However, the effects of BV on lung cancer cell growth have not been reported.
Kyung Eun Choi +11 more
doaj +1 more source
Materials & Design, 2021 Pancreatic cancer generates resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by downregulating death receptors and switching pro-apoptosis to anti-apoptosis through caspases blockers like X-linked inhibitor of apoptosis ...
Xianzhou Huang +9 more
doaj +1 more source
Emerging key roles for P2X receptors in the kidney [PDF]
, 2013 P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides.
Peppiatt-Wildman, Claire M. +10 more
core +1 more source
Child Death, Near Death and Stillbirth Commission Annual Report for Calendar Year 2013
, 2015 2013 annual report of the Child Death, Near Death and Stillbirth ...
Child Death, Near Death and Stillbirth Commission
core +2 more sources
Death Receptors: Signaling and Modulation
, 1998 REVIEW Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival.
Vishva M. Dixit, Avi Ashkenazi
core +1 more source
Filoviruses: Innate Immunity, Inflammatory Cell Death, and Cytokines
Pathogens, 2022 Filoviruses are a group of single-stranded negative sense RNA viruses. The most well-known filoviruses that affect humans are ebolaviruses and marburgviruses. During infection, they can cause life-threatening symptoms such as inflammation, tissue damage,
Jianlin Lu +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo +9 more
wiley +1 more source