Results 101 to 110 of about 49,393,497 (356)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Frontiers in Psychology, 2012 Near-death experiences (NDEs) are profound psychic experiences commonly occurring in life-threatening conditions. They include feeling a sense of peace, of seeing a bright light, encountering deceased relatives or religious figures, and of transcending ...
Enrico eFacco, Christian eAgrillo
doaj +1 more source
Circulation, 2018 Background: Studies of out-of-hospital cardiac arrest and sudden cardiac death (SCD) use emergency medical services records, death certificates, or definitions that infer cause of death; thus, the true incidence of SCD is unknown.
Z. Tseng +11 more
semanticscholar +1 more source
Urinary Tubular Injury Biomarkers Are Associated With ESRD and Death in the REGARDS Study. [PDF]
, 2018 IntroductionUrinary neutrophil gelatinase-associated lipocalin (uNGAL) and urinary kidney injury molecule-1 (uKIM-1) are established markers of subclinical acute kidney injury.
Bennett, Michael +10 more
core
Exposure to the complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis. [PDF]
, 2015 The loss of photoreceptors is the defining characteristic of many retinal degenerative diseases, but the mechanisms that regulate photoreceptor cell death are not fully understood.
Francesca Cordeiro, M +5 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
The problem of death in socio-humanitarian studies during the second half of the 20th century
Ученые записки Казанского университета: Серия Гуманитарные науки, 2017 The paper is devoted to the problem of death as a separate subject of socio-humanitarian studies in the West during the second half of the 20th century.
S.Yu. Malysheva
doaj
Posthuman Ecologies of the Corpse
Kvinder, Køn & Forskning, 2019 Book review of Erin E. Edwards: The Modernist Corpse: Posthumanism and the Posthumous. University of Minnesota Press, Minneapolis, 2018, 240 pages.
Marietta Radomska
doaj +1 more source
Journal of Near-Death Studies [PDF]
, 1999 Here we derive measures quantifying the information loss of a synaptic signal due to the presence of neuronal noise sources, as it electrotonically propagates along a weakly-active dendrite.
Koch, Christof, Manwani, Amit
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source