Results 111 to 120 of about 49,393,497 (356)
Community health workers and accountability: reflections from an international “think-in”
Community health workers (CHWs) are frequently put forward as a remedy for lack of health system capacity, including challenges associated with health service coverage and with low community engagement in the health system, and expected to enhance or ...
Marta Schaaf +12 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
ObjectivesTo assess the association between gender and suicide attempt/death and identify gender-specific risk/protective factors in adolescents/young adults. MethodsSystematic review (5 databases until January 2017).
A. Miranda-Mendizabal +17 more
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
NLRP3 inflammasome activation and cell death
Yi Huang, Wenjing Xu, Rongbin Zhou
semanticscholar +1 more source
Emerging functions of mammalian mitochondrial fusion and fission [PDF]
Mitochondria provide a myriad of services to the cell, including energy production, calcium buffering and regulation of apoptosis. How these diverse functions are coordinated among the hundreds of mitochondria in a given cell is largely unknown, but is ...
Chan, David C., Chen, Hsiuchen
core +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Studying autophagy’s relationship to cell death [PDF]
Depending on the circumstances, autophagy can prevent, cause or regulate the kinetics of cell death. Consequently, it is particularly important that experimental strategies to study these responses are designed carefully. Here, I discuss some of the issues to be considered when designing such experiments.
openaire +2 more sources
Non-vital staining, especially with rose Bengal, has been widely used in ecological studies to differentiate between the tests of dead(unstained) foraminifera from those presumed to be living at the time of collection (stained).
Bowser, S.S., Murray, J.W.
core
Metastasis and circulating tumor cells [PDF]
Cancer is a prominent cause of death worldwide. In most cases, it is not the primary tumor which causes death, but the metastases. Metastatic tumors are spread over the entire human body and are more difficult to remove or treat than the primary tumor ...
Dalum, G. van +2 more
core +1 more source

