Results 51 to 60 of about 410,324 (293)

Separation of microplastics from deep-sea sediment using an affordable, simple to use, and easily accessible density separation device

Microplastics and Nanoplastics
Microplastics accumulate in the environment but methods to extract particles from sediment for quantification and identification often lack accuracy and reproducibility.
Katherine R. Shaw, Rachel Sandquist, Cameron Fairclough, Jesse Black, Alexandra Fitzgerald, Jaxson T. Shaw, Scott Gallager, Jennifer Lynch   +7 more
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Planetesimals in Debris Disks [PDF]

, 2017
Planetesimals form in gas-rich protoplanetary disks around young stars. However, protoplanetary disks fade in about 10 Myr. The planetesimals (and also many of the planets) left behind are too dim to study directly. Fortunately, collisions between planetesimals produce dusty debris disks.
George H. Rieke, Andrew N. Youdin
openaire   +3 more sources

Coplanar circumbinary debris discs [PDF]

Monthly Notices of the Royal Astronomical Society, 2012
We present resolved Herschel images of circumbinary debris disks in the alpha CrB (HD139006) and beta Tri (HD13161) systems. We find that both disks are consistent with being aligned with the binary orbital planes. Though secular perturbations from the binary can align the disk, in both cases the alignment time at the distances at which the disk is ...
Kennedy, G. M.; Wyatt, M. C.; Sibthorpe, B.; Phillips, N. M.; Matthews, B. C.; Greaves, J. S.   +6 more
openaire   +5 more sources

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Bayesian Adaptive Extended Kalman-Based Orbit Determination for Optical Observation Satellites

Sensors
As the number of satellites and amount of space debris in Low-Earth orbit (LEO) increase, high-precision orbit determination is crucial for ensuring the safe operation of spacecraft and maintaining space situational awareness.
Yang Guo, Qinghao Pang, Xianlong Yin, Xueshu Shi, Zhengxu Zhao, Jian Sun, Jinsheng Wang   +6 more
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Hydrodynamic Ram Effect Caused by Debris Hypervelocity Impact on Satellite Tank

Applied Sciences, 2019
To study the hydrodynamic ram effect caused by the debris hypervelocity impact on the satellite tank, a numerical simulation of the spherical debris impacting the satellite tank at the velocity of 7000 m/s was carried out based on ANSYS/LS-DYNA software.
Beilei Zhao, Jiguang Zhao, Cunyan Cui, Yongsheng Duan   +3 more
doaj   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source