Results 131 to 140 of about 551,103 (329)

HD 117214 debris disk: scattered-light images and constraints on the presence of planets [PDF]

open access: green, 2020
N. Engler   +36 more
openalex   +1 more source

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

open access: yesAdvanced Science, EarlyView.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie   +5 more
wiley   +1 more source

Identifying and Characterizing Infrared Excesses in the Spitzer Kepler Survey (SpiKeS)

open access: yesThe Astrophysical Journal
We report our search for infrared excesses in the Spitzer/Infrared Array Camera survey of the Kepler field at 3.6 and 4.5 μ m. The Spitzer Kepler Survey contains ∼190,000 targets, which we reduce to ∼117,000 targets after applying multiple filters to ...
Sydney O. Skorpen   +4 more
doaj   +1 more source

Debris Disks: Seeing Dust, Thinking of Planetesimals and Planets

open access: yes, 2010
Debris disks are optically thin, almost gas-free dusty disks observed around a significant fraction of main-sequence stars older than about 10 Myr. Since the circumstellar dust is short-lived, the very existence of these disks is considered as evidence ...
Akeson   +131 more
core   +1 more source

In Situ Engineering of Tumor Cells as Self‐Sustaining cDC1 Programming Factories for Effective Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The fused EV platform AS16‐EL@MPLA/p‐FX reprograms tumor cells into cytokine‐producing factories that continuously secrete XCL1 and FLT3L to recruit and differentiate cDC1s, while embedded MPLA activates them through TLR4 signaling and AS16 prevents their exhaustion, thereby enhancing antitumor immunity and establishing durable immune memory against ...
Shuiling Jin   +16 more
wiley   +1 more source

MINDS: Detection of an Inner Gas Disk Caused by Evaporating Bodies around HD 172555

open access: yesThe Astrophysical Journal
Mechanisms such as collisions of rocky bodies or cometary activity give rise to dusty debris disks. Debris disks trace the leftover building blocks of planets, and thus also planetary composition.
Matthias Samland   +25 more
doaj   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

open access: yesAdvanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha   +12 more
wiley   +1 more source

The Search for Disk Perturbing Planets Around the Asymmetrical Debris Disk System HD 111520 Using REBOUND

open access: yesThe Astrophysical Journal
Debris disks, which are optically thin, dusty disks around main-sequence stars, are often found to have structures and/or asymmetries associated with planet–disk interactions.
Katie A. Crotts, Brenda C. Matthews
doaj   +1 more source

Assessing the Nature of Human Brain‐Derived Extracellular Vesicles on Synaptic Activity Via the Development of an Air‐liquid Microfluidic Platform

open access: yesAdvanced Science, EarlyView.
This seminal study highlights the interwoven and tightly regulated functions of brain‐derived extracellular vesicles. Using microfluidics, proteomics, and AI‐based electric signal analyses of cortical brain explants, this work provides a useful resource dataset revealing the composition of human brain‐derived extracellular vesicles obtained from ...
Corentin Bernou   +14 more
wiley   +1 more source

Extending the ALMA Census of Circumstellar Disks in the Upper Scorpius OB Association

open access: yesThe Astrophysical Journal
We present Atacama Large Millimeter/submillimeter Array (ALMA) Band 7 continuum (340 GHz) and carbon monoxide (CO) J = 3–2 observations for an extended sample of disks in the Upper Scorpius OB Association (Upper Sco, age ∼10 Myr).
John M. Carpenter   +4 more
doaj   +1 more source

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