Results 111 to 120 of about 210,786 (294)

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

High Resolution ALMA Data of the Fomalhaut Debris Disk Confirms Apsidal Width Variation

The Astrophysical Journal Letters
We present long-baseline observations of the Fomalhaut outer debris disk at 223 GHz (1.3 mm) from Atacama Large Millimeter/submillimeter Array (ALMA) Cycle 5, which we use along with archival short-baseline observations to produce a 0 $\mathop{.}\limits{^
Jay S. Chittidi, Meredith A. MacGregor, Joshua Bennett Lovell, Gaspard Duchene, Mark Wyatt, Olja Panic, Paul Kalas, Margaret Pan, A. Meredith Hughes, David J. Wilner, Grant M. Kennedy, Luca Matrà, Michael P. Fitzgerald, Kate Y. L. Su   +13 more
doaj   +1 more source

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

Deep Search for a Scattered Light Dust Halo Around Vega with the Hubble Space Telescope

The Astronomical Journal
We present a provisory scattered-light detection of the Vega debris disk using deep Hubble Space Telescope (HST) coronagraphy (PID 16666). At only 7.7 pc, Vega is immensely important in debris disk studies both for its prominence and also because it ...
Schuyler G. Wolff, András Gáspár, George H. Rieke, Jarron M. Leisenring, Kate Su, David J. Wilner, Luca Matrà, Marie Ygouf, Nicholas P. Ballering   +8 more
doaj   +1 more source

Identification of senescence‐related genes in Parkinson's disease reveals candidate therapeutic targets and pathological processes

Animal Models and Experimental Medicine, EarlyView.
At the genomic level, a large number of differentially expressed genes (DEGs) and aging‐related DEGs have been screened. Ten hub genes, such as IFNγ and IRF7, have been identified and shown potential value in the diagnosis of PD, holding promise as novel biomarkers to facilitate early and precise diagnosis.
Haojie Wu, Tingting Liu, Xiangshu Cheng, Jianshe Wei   +3 more
wiley   +1 more source

Revisiting the Ultraviolet Spectroscopy of the η Tel Edge-on Debris Disk

The Astronomical Journal
We revisit the ultraviolet absorption spectroscopy of the edge-on debris disk surrounding the A0V star η  Telescopii. Previous work found absorption components at four velocities (∼−23, −18, −10, −1 km s ^−1 ), with the most blueshifted component (−23 km
Allison Youngblood, Alexis Brandeker, Sebastián Pérez, Aki Roberge, Alycia Weinberger, Meredith A. MacGregor, Barry Welsh   +6 more
doaj   +1 more source

Developmental morphology of claspers and clasper‐glands during maturation in Potamotrygon wallacei (Chondrichthyes: Potamotrygoninae)

The Anatomical Record, EarlyView.
Abstract The claspers are the copulatory organs in male elasmobranchs, responsible for directing the semen into the female cloaca (C). However, the microscopic morphology of the claspers remains poorly understood. This study describes the morphology of the claspers and clasper glands (CGs) of cururu stingray (Potamotrygon wallacei) at different ...
Matheus Samuel Cunha Braga, Grazyelle Sebrenski da Silva, Maria Inês Braga de Oliveira, Jaydione Luiz Marcon, Ruben Dario Morales Gamba   +4 more
wiley   +1 more source

Probing the Era of Giant Collisions: Millimeter Observations of the HD 166191 System

The Astrophysical Journal
We present nonsimultaneous Atacama Large Millimeter/submillimeter Array (ALMA) Band 7 and Submillimeter Array (SMA) observations of the HD 166191 disk, which was recently thought to have a collision in its terrestrial planet zone.
Kadin Worthen, Christine H. Chen, A. Meredith Hughes, Brandon C. Johnson, Isabel Rebollido, Diego E. Garcia, Jamar Kittling, Carey M. Lisse   +7 more
doaj   +1 more source

Enhancing Anode‐Free Lithium Metal Batteries: A Lightweight MPTS‐MXene Current Collector for Superior Performance and Energy Density

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study introduces an MPTS‐modified MXene current collector for anode‐free lithium metal batteries (AFLMBs). A key advantage of MPTS‐MXene is its ultralight weight, only 15% as heavy as standard copper per unit volume. Its special layered structure and Si‐O rich surface help lithium deposit smoothly and flat, while forming a protective layer that ...
Jiawei Ren, Jiayi Zhang, Jingchao Zhang, Jianbo Li, Yonas Tsegaye Megra, Jianchuan Wang, Yong Du, Rong Huang, Yi Cui, Chenguang Liu, Li Yang   +10 more
wiley   +1 more source

ASASSN-24fw: Candidate Gas-rich Circumsecondary Disk Occultation of a Main-sequence Star

The Astronomical Journal
Dusty disks around planetary and substellar companions in outer reaches of exoplanetary systems can be detected as long-lasting occultations, provided the observer is close to the secondary’s orbital plane. Here we report optical spectroscopy with KOSMOS
Nadia L. Zakamska, Gautham Adamane Pallathadka, Dmitry Bizyaev, Jaroslav Merc, James E. Owen, Henrique Reggiani, Kevin C. Schlaufman, Karolina Bąkowska, Sławomir Bednarz, Krzysztof Bernacki, Agnieszka Gurgul, Kirsten R. Hall, Franz-Josef Hambsch, Barbara Joachimczyk, Krzysztof Kotysz, Sebastian Kurowski, Alexios Liakos, Przemysław J. Mikołajczyk, Erika Pakštienė, Grzegorz Pojmański, Adam Popowicz, Daniel E. Reichart, Łukasz Wyrzykowski, Justas Zdanavičius, Michał Żejmo, Paweł Zieliński, Staszek Zola   +26 more
doaj   +1 more source