Results 171 to 180 of about 6,888 (239)

Effect of C5a Receptor Antagonist on the Osteogenic Differentiation of Dental Pulp Stem Cells

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objective Complement component 5a (C5a) binding to its receptor (C5aR) can mediate pro‐inflammatory immune responses, which impairs osteogenic differentiation of dental pulp stem cells (DPSCs). The present study aimed to evaluate the regulatory effect of C5aR antagonist (W54011) on the osteogenic differentiation of DPSCs in an in vitro ...
Xiaohan Tan   +7 more
wiley   +1 more source

Critical role of keratinocytes and protease‐activated receptor 2 in secondary lymphedema development

open access: yesClinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Activated keratinocytes play an important role in the early stage of the pathophysiology of secondary lymphedema through PAR2 signaling. Lymphatic injury‐induced protease activation stimulates keratinocyte PAR2 signaling, driving hyperkeratosis and Th2 inflammation, which can be therapeutically attenuated by teriflunomide. Abstract Background Secondary
Hyeung Ju Park   +18 more
wiley   +1 more source

Decalcify cardiac CT: unveiling clearer images with deep convolutional neural networks. [PDF]

open access: yesFront Med (Lausanne)
Nagarajan G   +8 more
europepmc   +1 more source

Bone Healing Response of Two Different Silicate‐Containing Calcium Phosphate Synthetic Bone Grafts in a Rabbit Femoral Critical‐Sized Defect Model

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 6, June 2026.
ABSTRACT Synthetic materials based on calcium phosphates (CaP) are frequently used as bone graft substitutes when natural bone grafts are not available or not suitable. One approach used to enhance their performance is the incorporation of ions such as silicate ions, which are known to support osteointegration by stimulating bone formation. The present
Iain R. Gibson   +7 more
wiley   +1 more source

Visualizing the Achilles Tendon Enthesis: Translational Insights from 7-Tesla MR Microscopy and Histology. [PDF]

open access: yesDiagnostics (Basel)
Mittendorfer JM   +5 more
europepmc   +1 more source

Resorption Pattern and Bone Regeneration Using a Synthetic Bone Substitute Block With or Without rhBMP‐2 and Bisphosphonates: An in Vivo Experiment

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 6, June 2026.
ABSTRACT This study aimed to investigate whether recombinant human bone morphogenetic protein‐2 (rhBMP‐2) or bisphosphonate added to synthetic block bone substitute influences new bone formation and grafting material degradation patterns. In a rabbit calvarial model, four critical‐size bone defects were created and treated with a saline‐soaked ...
Seung Ha Yoo   +6 more
wiley   +1 more source

Engineered Nestin+ TSPC‐Derived Exosomes Promote Tendon Repair Via Metabolic Reprogramming

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Engineered Nestin+ TSPC‐derived exosomes promote tendon repair by reprogramming tenocyte metabolism via the pantothenate‐CoA‐mitochondria axis. They enhance mitochondrial function, reduce senescence and oxidative stress, restoring tendon structure and function in injured and aged models.
Linxiang Cheng   +8 more
wiley   +1 more source

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