Results 191 to 200 of about 6,888 (239)

Intramuscular neural distribution of the soleus for botulinum neurotoxin injection: application to spasticity. [PDF]

Sci Rep
Yi KH, Hu H, Hwang SO, Lee JH, Lee HJ.
europepmc   +1 more source

Senescent BMSC‐Derived Thbs1 Drives Inflammaging and Impairs Bone Regeneration by Suppressing PINK1/Parkin‐Mediated Mitophagy in Macrophages

Aging Cell, Volume 25, Issue 6, June 2026.
Aging BMSC‐derived Thbs1 activates the macrophage TGF‐β/Smad3 pathway to transcriptionally repress Pink1, impairing mitophagy and causing mitochondrial ROS accumulation. This redox imbalance drives M1 polarization and IL‐6 secretion. IL‐6 feeds back to BMSCs via the JAK/STAT3 pathway to inhibit osteogenesis and upregulate Thbs1, establishing a self ...
Yifeng Xing, Jingjing Su, Yanjun Lin, Nengwen Huang, Sihui Zhang, Yuwei Zhou, Jie Lu, Weiping Chen, Kaixun He, Wenxiu Yuan, Yang Li, Geyuan Zheng, Pengyuan Hu, Dong Wu, Yanjing Ou, Jiang Chen   +15 more
wiley   +1 more source

Utilization of ultrasonic aspirator for combined aortic and mitral valve decalcification: a case study. [PDF]

J Cardiothorac Surg
Alomari M, Paciotti B, Garg P, Noor S, Celik NB, Sareyyupoglu B.   +5 more
europepmc   +1 more source

Trastuzumab Deruxtecan for HER2‐Low Metastatic Breast Cancer: Practical Considerations for Medical Oncologists and Pathologists in Australia

Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 3, Page 381-391, June 2026.
ABSTRACT Trastuzumab deruxtecan (T‐DXd) is a third‐generation, HER2‐targeting antibody‐drug conjugate that has been shown to significantly prolong overall survival, compared with standard chemotherapy, when used to treat patients who have “HER2‐low” (HER2 immunohistochemistry [IHC] score 1+; or HER2 IHC 2+ plus in situ hybridization‐negative ...
Andrew Redfern, Elgene Lim, Sunil Lakhani, Nirmala Pathmanathan, Sudarsha Selva‐Nayagam, Nicole McCarthy, Belinda Yeo, Benjamin Dessauvagie, Gelareh Farshid   +8 more
wiley   +1 more source

One protocol to rule them all: a pilot study to identify the best fixation and decalcification approach for bone marrow biopsy immunohistochemistry. [PDF]

Pathologica
Paudice M, Gambella A, Pigozzi S, Campora M, Pitto F, Bozzano S, Mastracci L, Grillo F.   +7 more
europepmc   +1 more source

The wide gape of snakes: A comparison of the developing mandibular symphysis in sauropsids

Journal of Anatomy, Volume 248, Issue 6, Page 937-949, June 2026.
Our analysis explores the adaptations at the mandibular symphysis required to allow extreme lower jaw mobility in macrostomate snakes taking a comparative approach. Abstract The origin and evolution of snakes has been marked by the acquisition of many morphological and functional novelties, one of which is the possession of a highly kinetic skull ...
Maricci Basa, Neal Anthwal, Ryan N. Felice, Abigail S. Tucker   +3 more
wiley   +1 more source

Spatial transcriptomics: challenges and future directions in musculoskeletal diseases. [PDF]

Curr Opin Rheumatol
Delos Santos K, Rockel JS, Kapoor M.
europepmc   +1 more source

Distal femur osteosarcoma in an adolescent: Limb salvage with cryosurgery-recycled bone, hemi knee replacement, and ORIF-A case report. [PDF]

Int J Surg Case Rep
Primayudha B, Budi MNS, Wijaya W, Mas'ud MS.   +3 more
europepmc   +1 more source

Recent Advances in Drug Delivery and Oral Health: The Impact of Technology and Digital Advances as a New Frontier. [PDF]

Bioengineering (Basel)
Grippaudo C, Nucci L, Farronato M.
europepmc   +1 more source

Multidisciplinary international expert consensus recommendations on tissue acquisition in non-small cell lung cancer. [PDF]

EBioMedicine
Lee P, Abdelhamid K, Butler R, Cooper W, Nagasaka M, Peters S, Seijo L, Silvestri G, Wee B, Yasufuku K, Navani N.   +10 more
europepmc   +1 more source