Results 41 to 50 of about 948 (102)

The Use of Affinity Gels for the Study of the Ligand Binding Properties of Mammalian Acetylcholinesterase [PDF]

open access: yes, 1975
An affinity adsorption technique for the analysis of the binding sites of acetylcholinesterase for small ligands is presented. By studying the interaction of decamethonium and edrophonium the second anionic binding site of decamethonium ds characterized ...
Bertil Niklasson, Gunnar Hollunger
core   +1 more source

Pharmacology of Organic Cation Transporters: Focus on Structure-Function Relationships in OCT3 (SLC22A3) [PDF]

open access: yes, 2015
Organic Cation Transporters (OCTs) are polyspecific, facilitative transporters that play major roles in metabolite and drug clearance. OCTs are promising drug targets and elucidating their mechanisms of substrate recognition is crucial for rational drug ...
Li, Dan C
core   +1 more source

Epoxyeicosatrienoic acids are involved in the C70 fullerene derivative–induced control of allergic asthma [PDF]

open access: yes, 2012
Background: Fullerenes are molecules being investigated for a wide range of therapeutic applications. We have shown previously that certain fullerene derivatives (FDs) inhibit mast cell (MC) function in vitro, and here we examine their in vivo ...
Kepley, Christopher   +1 more
core  

The role of 5-HT2 receptors in central cardiovascular regulation in anaesthetized rats. [PDF]

open access: yes, 1999
Previous studies have demonstrated that activation of central 5-HT2 receptors in anaesthetized and unanaesthetized rats causes the release of vasopressin and a rise in arterial blood pressure (Anderson et al., 1992, Pérgola et al., 1993).
Knowles, Ian David
core  

Conjugates of Methylene Blue with Cycloalkaneindoles as New Multifunctional Agents for Potential Treatment of Neurodegenerative Disease. [PDF]

open access: yesInt J Mol Sci, 2022
Bachurin SO   +18 more
europepmc   +1 more source

A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE). [PDF]

open access: yesJ Enzyme Inhib Med Chem, 2022
Evangelista TCS   +8 more
europepmc   +1 more source

A twenty-year journey exploring coumarin-based derivatives as bioactive molecules. [PDF]

open access: yesFront Chem, 2022
Pisani L   +8 more
europepmc   +1 more source

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