Results 21 to 30 of about 90,046 (287)

Metabolism of Tryptophan in the Liver: Interference with Decarboxylation of Other Aromatic Amino Acids

open access: yesActa Medica, 2000
Decarboxylation of aromatic amino acid in mammalian tissues is catalyzed by aromatic amino acid decarboxylase (EC. 4.1.1.28, AAD). The enzyme differs in its affinity to individual aromatic amino acids, the best substrates being 3,4-dihydroxyphenylalanine
Jaroslav Dršata, Eliška Marklová
doaj   +1 more source

Biological Activity of Cannabis sativa L. Extracts Critically Depends on Solvent Polarity and Decarboxylation

open access: yesSeparations, 2020
Minor cannabinoid and non-cannabinoid molecules have been proposed to significantly contribute to the pharmacological profile of cannabis extracts. Phytoplant Research has developed highly productive cannabis cultivars with defined chemotypes, as well as
Guillermo Moreno-Sanz   +4 more
doaj   +1 more source

An Adaptation To Life In Acid Through A Novel Mevalonate Pathway. [PDF]

open access: yes, 2016
Extreme acidophiles are capable of growth at pH values near zero. Sustaining life in acidic environments requires extensive adaptations of membranes, proton pumps, and DNA repair mechanisms.
Bowie, James U   +3 more
core   +1 more source

In Situ Decarboxylation-Pressurized Hot Water Extraction for Selective Extraction of Cannabinoids from Cannabis sativa. Chemometric Approach

open access: yesMolecules, 2021
Isolation of the therapeutic cannabinoid compounds from Cannabis Sativa L. (C. Sativa) is important for the development of cannabis-based pharmaceuticals for cancer treatment, among other ailments.
Yannick Nuapia   +4 more
doaj   +1 more source

Amine-Catalyzed Decarboxylative Aldol Reaction of β-Ketocarboxylic Acids with Trifluoropyruvates

open access: yesMolecules, 2019
Decarboxylative aldol reaction of aliphatic carboxylic acids is a useful method for C−C bond formation because carboxylic acids are an easily available class of compounds. In this study, we found that the decarboxylative aldol reaction of tertiary &
Ryouta Kawanishi   +3 more
doaj   +1 more source

Effect of methyl substituent on the solubility of 1,4-benzoquinone derivatives in n-octanol/water system

open access: yesJurnal Kimia Sains dan Aplikasi, 2020
The solubility of the compound is a crucial task for new drug design. Quinone is a promising candidate to develop as a new drug. In this research, the synthesis of 1,4-benzoquinone derivatives, that is, 2-(5-bromoamyl)-3,5-dimethyl-1,4-benzoquinone (2a ...
Siti Mariyah Ulfa   +3 more
doaj   +1 more source

Characteristics of C-4 photosynthesis in stems and petioles of C-3 flowering plants [PDF]

open access: yes, 2002
Most plants are known as C-3 plants because the first product of photosynthetic CO2 fixation is a three-carbon compound. C-4 plants, which use an alternative pathway in which the first product is a four-carbon compound, have evolved independently many ...
A Ben Zioni   +29 more
core   +1 more source

Identification of SARS-CoV-2 Main Protease Inhibitors from a Library of Minor Cannabinoids by Biochemical Inhibition Assay and Surface Plasmon Resonance Characterized Binding Affinity

open access: yesMolecules, 2022
The replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by its main protease (Mpro), which is a plausible therapeutic target for coronavirus disease 2019 (COVID-19). Although numerous in silico studies reported the
Chang Liu   +5 more
doaj   +1 more source

A Substrate-induced Biotin Binding Pocket in the Carboxyltransferase Domain of Pyruvate Carboxylase [PDF]

open access: yes, 2013
Biotin-dependent enzymes catalyze carboxyl transfer reactions by efficiently coordinating multiple reactions between spatially distinct active sites. Pyruvate carboxylase (PC), a multifunctional biotin-dependent enzyme, catalyzes the bicarbonate- and ...
Lietzan, Adam D, Maurice, Martin St.
core   +2 more sources

Visible-Light-Induced Decarboxylation of Dioxazolones to Phosphinimidic Amides and Ureas

open access: yesMolecules, 2022
A visible-light-induced external catalyst-free decarboxylation of dioxazolones was realized for the bond formation of N=P and N–C bonds to access phosphinimidic amides and ureas. Various phosphinimidic amides and ureas (47 examples) were synthesized with
Jie Pan   +4 more
doaj   +1 more source

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