Results 81 to 90 of about 939,083 (294)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

The influence of TiO2 nanoparticle incorporation on surface potential decay of corona-resistant polyimide nanocomposite films

open access: yes, 2011
PI nanocomposite films containing surface modified nanoparticles by employing silane coupling agent were prepared using in-situ dispersion polymerization process.
Dang, Zhimin   +3 more
core   +1 more source

Decay of Electric Charge on Corona Charged Polyethylene

open access: yes, 2008
In this paper, the surface potential decay of corona-charged low density polyethylene (LDPE) films has been investigated. It has been found that for the same sample thickness the faster decay occurs in the sample with a higher charging voltage.
Xu, Zhiqiang   +2 more
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

eDNA State and Medium Affect DNA Degradation Patterns in Seminatural Systems of Southern African Waterholes

open access: yesEnvironmental DNA
Environmental DNA (eDNA) has evolved into a valuable asset of the ecologists' toolkit, enabling time‐ and cost‐efficient biodiversity assessments in a wide variety of ecosystems.
Irmgard Sedlmayr, Tamara Schenekar
doaj   +1 more source

Railroad revolution: infrastructural decay and modernization in Argentina

open access: yesTapuya, 2019
How does modernity arrive and take hold? In this article, I examine efforts by the recent administration of Cristina Fernández de Kirchner to modernize railroad infrastructure in Argentina amidst ongoing decay.
Stephanie McCallum
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Coarse woody debris carbon stocks in natural spruce forests of Babia hora

open access: yesJournal of Forest Science, 2010
Although coarse woody debris (CWD) represents one of the major carbon pools in natural forest ecosystems, little information is available about its CWD carbon stocks.
K. Merganičová, J. Merganič
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

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