Results 61 to 70 of about 964,892 (304)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Implication of anaerobic and aerobic decomposition of Eichhornia azurea (Sw.) Kunth. on the carbon cycling in a subtropical reservoir

Brazilian Journal of Biology
This study aimed at describing kinetic aspects of aerobic and anaerobic mineralization of Eicchornia azurea. The samples of aquatic macrophyte and water were collected in the Monjolinho Reservoir (22° 00′ S and 47° 54′ W).
I Bianchini Junior, MB Cunha-Santino, JU Ribeiro, DGB Penteado   +3 more
doaj   +1 more source

Uniform decay estimates for the semi-linear wave equation with locally distributed mixed-type damping via arbitrary local viscoelastic versus frictional dissipative effects

Advances in Nonlinear Analysis, 2023
We are concerned with the stabilization of the wave equation with locally distributed mixed-type damping via arbitrary local viscoelastic and frictional effects.
Jin Kun-Peng, Wang Li
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

In vitro activity of some essential oils against Penicillium digitatum

Advances in Horticultural Science, 2018
Natural plant essential oils (EOs) can be used instead of synthetic fungicides because of human health concerns and environmental protection. In this study, the in vitro activity of some plants EOs against Penicillium digitatum, the cause of citrus green
Fereshteh Khorram, Asghar Ramezanian, Mohammad Jamal Saharkhiz   +2 more
doaj   +1 more source

On the Decay of Crossing Numbers [PDF]

Journal of Combinatorial Theory, Series B, 2007
Let \(\text{cr}(G)\) denote the crossing number of the graph \(G\). \textit{B. Richter} and \textit{C. Thomassen} [J. Comb. Theory, Ser. B 58, 217--224 (1993; Zbl 0733.05035)] conjectured that there is a constant \(c\) such that every graph \(G\) with crossing number \(k\) has an edge \(e\) such that \(\text{cr}(G-e)\geq k-c\sqrt{k}\), and showed that ...
Jacob Fox, Csaba D. Tóth
openaire   +3 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Effectiveness of Several GRAS Salts against Fungal Rot of Fruit after Harvest and Assessment of the Phytotoxicity of Sodium Metabisufite in Treated Fruit

Journal of Fungi
This study evaluates the efficacy of the salts sodium metabisulfite (SMB), ammonium bicarbonate, sodium bicarbonate, and potassium dihydrogen orthophosphate first in vitro against the main postharvest fruit rot fungi, Alternaria alternata, Botrytis ...
Mohamed Bechir Allagui, Mouna Ben Amara
doaj   +1 more source

Muon decay [PDF]

Zeitschrift für Physik C Particles and Fields, 1992
The decay of the muon has been studied at PSI with several precision measurements: The longitudinal polarization P_{\mathrm{L}}(E) P
openaire   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source