Results 61 to 70 of about 939,083 (294)

Effect of Stenotrophomonas maltophilia on Tuberculosis

open access: yesMicrobiology Spectrum, 2023
Tuberculosis (TB) is an important infectious disease suffered by many countries, including China. In this stage, accurate diagnosis and treatment are key measures for the prevention and control of TB.
Yue Li   +7 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Role of Wind Shear in the Decay of Convective Boundary Layers

open access: yesAtmosphere, 2020
The role of wind shear in the decay of the convective boundary layer (CBL) is systematically investigated using a series of large-eddy simulations. Nine CBLs with weak, intermediate, and strong wind shear are simulated, and their decays after stopping ...
Seung-Bu Park   +2 more
doaj   +1 more source

Comparative performance of pxts versus creosote in an awpa e7 field stake test

open access: yesMaderas: Ciencia y Tecnología, 2021
A need exists to develop new organic, environmentally benign wood preservatives for industrial applications to replace the older creosote and pentachlorophenol systems.
Darrel D. Nicholas   +2 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

When wood cladding degenerates

open access: yesFORMakademisk, 2023
For several decades, the mechanisms of decay of wood exposed outdoor have been scrutinized in order to ameliorate the performances of this versatile material when used for purposes such as house cladding.
Géraldine Brun
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

STALINGRAD: DESTROYED AND REVIVED / СТАЛИНГРАД: РАЗРУШЕННЫЙ И ВОЗРОЖДЕННЫЙ [PDF]

open access: yesСоциология города, 2018
The article deals with the problems of preservation of the architectural objects of Stalingrad after the end of the battle on the Volga river. The authors analyze the results of the examination of buildings in the central part of the city (Ermansky ...
P. P. Oleinikov / П. П. Олейников   +1 more
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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