Results 41 to 50 of about 467,494 (290)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Monopodial and Sympodial Bamboos Grown in Tropic and Sub-tropic Countries – A Review

open access: yesBioResources, 2023
Bamboo belongs to the grass family and is an important non-timber forest product in tropic and sub-tropic countries. The global trade of bamboo products is worth billions of dollars and is mainly dominant with monopodial bamboo grown in sub-tropic ...
Norul Hisham Hamid   +3 more
doaj   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Tree crown architecture: a tool for decay resistance evaluation [PDF]

open access: yes, 2013
The variability of natural durability contributes to the bad perception of some wood end-users. In our search, we need to adjust our methods and strategies to estimate natural durability and extract higher value from wood resources.
Amissa Adima, Augustin   +5 more
core  

Quantum Superinductor with Tunable Non-Linearity [PDF]

open access: yes, 2012
We report on the realization of a superinductor, a dissipationless element whose microwave impedance greatly exceeds the resistance quantum. The design of the superinductor, implemented as a ladder of nanoscale Josephson junctions, enables tuning of the ...
Bell, M. T.   +4 more
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Effect of cell wall modification of styrene wood polymer with maleic anhydride and glycidyl methacrylate on thermal stability, mechanical behavior and biological resistance of composite [PDF]

open access: yesIranian Journal of Wood and Paper Industries, 2017
This research was investigated the effect of maleic anhydride and glycidyl methacrylate on thermal stability, mechanical behavior and biological resistance of hornbeam wood polymer containing styrene monomer.
maryam ghorbani   +2 more
doaj  

Aging process of electrical contacts in granular matter

open access: yes, 2003
The electrical resistance decay of a metallic granular packing has been measured as a function of time. This measurement gives information about the size of the conducting cluster formed by the well connected grains. Several regimes have been encountered.
Avrami   +18 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Tuning the Correlation Decay in the Resistance Fluctuations of Multi-Species Networks

open access: yes, 2009
A new network model is proposed to describe the $1/f^\alpha$ resistance noise in disordered materials for a wide range of $\alpha$ values ($0< \alpha < 2$).
Bid A   +18 more
core   +1 more source

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