Results 31 to 40 of about 135,835 (253)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Effect of cell wall modification of styrene wood polymer with maleic anhydride and glycidyl methacrylate on thermal stability, mechanical behavior and biological resistance of composite [PDF]

Iranian Journal of Wood and Paper Industries, 2017
This research was investigated the effect of maleic anhydride and glycidyl methacrylate on thermal stability, mechanical behavior and biological resistance of hornbeam wood polymer containing styrene monomer.
maryam ghorbani, Farzaneh Heydari, seyed Majid Zabihzadeh   +2 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Valorization of moroccan olive stones by using it in particleboard panels

Maderas: Ciencia y Tecnología, 2014
The main objective of this work was to find new applications to valorize olive stones (endocarp and seed). In order to improve knowledge on olive stones, the phenolic compounds concentration of three varieties of Moroccan olive trees: Moroccan Picholine,
M. Elbir, A. Moubarik, E.M. Rakib, N. Grimi, A. Amhoud, G. Miguel, H. Hanine, J. Artaud, P. Vanloot, M. Mbarki   +9 more
doaj  

Decay and termite resistance of phthaloylated wood

Wood Preservation, 2008
スギ辺材を無水フタル酸で化学修飾することによって得られたフタル化木材の耐朽性と耐蟻性を, アセチル化木材と比較しながら評価した。褐色腐朽菌オオウズラタケと白色腐朽菌カワラタケによる腐朽試験の結果, フタル化木材は, アセチル化木材よりも軽度な置換基導入で, 高い耐朽性を示すことが明らかとなり, その効果は特にオオウズラタケに対して顕著であった。このような高い耐朽性を付与するのに必要な置換基の分子構造の特徴を調べるために, フタル基と類似の構造を有する化学修飾木材を調製し, それらの耐朽性を調べた。その結果, 無水トリメリト酸がフタル化に匹敵する高い耐朽性を付与したのに対して, 無水安息香酸やcis-1, 2-シクロヘキサンジカルボン酸無水物では, 顕著な耐朽性が得られることはなく ...
NAGASAWA, Yoko, KODACHI, Rie, SHIBUTANI, Sakae, HABU, Naoto   +3 more
openaire   +2 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Variation in the decay resistance of larch to fungi

Annals of Forest Science, 2008
* La résistance à la dégradation du bois de duramen du mélèze (Larix sp.) est évaluée à partir d'un échantillon d'éprouvettes extraites de 313 arbres appartenant à 3 espèces (L. decidua, L. kaempferi et leur hybride), 3 races de mélèze européen (polonica, sudetica et alpine) et 13 lots différents.
Curnel, Yannick, Jacques, Dominique, Gierlinger, Notburga, Pâques, Luc   +3 more
openaire   +6 more sources