Results 51 to 60 of about 58,315 (262)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Architecture and Engineering, 2016 Increase in the number of two-wheeled motor vehicles (motorcycles, vehicles of category L3) is observed in the traffic of almost all countries in the world. That is why the number of victims and people seriously injured in the road traffic accidents (RTA)
Stanislav Evtyukov +2 more
doaj +1 more source
New Journal of Physics, 2009 A microstructured array of 1254 electrodes on a substrate has been configured to generate an array of local minima of electric field strength with a periodicity of 120 $μ$m about 25 $μ$m above the substrate. By applying sinusoidally varying potentials to the electrodes, these minima can be made to move smoothly along the array.
Meek, S., Conrad, H., Meijer, G.
openaire +4 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Acceleration (Deceleration) Model Supporting Time Delays to Refresh Data
Promet (Zagreb), 2018 This paper proposes a mathematical model to regulate the acceleration (deceleration) applied by self-driving vehicles in car-following situations.
José Gerardo Carrillo González +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
SportsChange-of-direction (COD) ability is a key determinant of performance in youth basketball, yet the relative contribution of braking, re-acceleration, trunk motion, and body composition remains unclear.
Áron Mészáros +5 more
doaj +1 more source
How do Today's Modern Passenger Cars Brake?
Logi, 2018 The article deals with issues of vehicle braking from different points of view. We made repeated braking tests of modern vehicles during intensive braking on various asphalt surfaces with the goal to evaluate character of this random variable.
Ondruš Ján +3 more
doaj +1 more source