Results 61 to 70 of about 58,315 (262)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Caffeine supplementation improved movement patterns and reactive agility in rugby sevens matches in male collegiate players

open access: yesJournal of the International Society of Sports Nutrition
Purpose Rugby sevens is a high-intensity contact sport often played in two-day tournaments. Caffeine is widely used by rugby players for its performance-enhancing effects.
Chang-Li Hsueh   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Phase-specific changes in running velocity during the 100 m sprint in university athletes

open access: yesPhysical Education of Students
Background and Study Aim. The 100 m sprint is widely used as an indicator of human neuromuscular performance and maximal running speed. Sprinting over this distance is characterized by distinct phases, including acceleration, maximum velocity, and ...
Md. Eman Ali   +3 more
doaj   +1 more source

Deceleration

open access: yes, 2022
Modern society is characterised by increased velocity and instability, i.e., it is becoming increasingly liquid and socially accelerated (Bauman, 2012; Rosa, 2013). Herein, the concept of self and relationships with others or their surroundings are constantly changing for consumers.
openaire   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Acute Effects of Ankle Tissue Flossing on Countermovement Jump Braking Strategy and Passive Mechanical Properties Following Repeated Jumping Exercise

open access: yesApplied Sciences
Effects of calf and ankle tissue flossing on countermovement jump (CMJ) braking strategy and local passive mechanical properties were examined after repeated jumping.
Hung-Wei Cheng   +5 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Estimation of car braking parameters

open access: yesLietuvos Matematikos Rinkinys, 2004
In the paper the problem of prediction of car braking distance from its initial speed is considered. Based on the data of braking experiments, a regression model is fitted and validated and the covariance structure of the prediction errors is ...
Marijus Radavičius, Saulius Nagurnas
doaj   +1 more source

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