Results 101 to 110 of about 12,375 (249)

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Hydrogels in Periodontal and Craniofacial Regeneration: Current Applications and Next‐Generation Biomaterials

Journal of Periodontal Research, EarlyView.
Hydrogel‐based therapies have proven to be valuable tools to address the unique regeneration challenges of complex multi‐domain periodontal and craniofacial tissues. This review highlights and classifies clinically approved and emerging hydrogel therapies indicated for the regeneration of periodontal and craniofacial tissues.
Z. Gouveia, M. Diba, B. T. Yilmaz, Jae‐Kook Cha, D. T. Wu, D. J. Mooney   +5 more
wiley   +1 more source

Development of a supercritical CO2 decellularization technology [PDF]

Decellularization of mammalian tissue describes the process by which cellular materials are removed from the extracellular matrix (ECM, Hinderer, Layland and Schenke-Layland, 2016).
Loczenski, Rabea
core   +3 more sources

Soft Tissue Substitutes: Current Biomaterials and Indications at Teeth and Implant Sites

Journal of Periodontal Research, EarlyView.
This manuscript provides an updated overview of the current evidence on soft tissue graft substitutes for teeth and dental implants. When appropriately indicated, these biomaterials offer a reliable, less invasive alternative to autogenous grafts, effectively improving root coverage, keratinized mucosa width, and soft tissue thickness with reduced ...
Lorenzo Tavelli, Daniel Thoma, Maria Elisa Galarraga‐Vinueza, Mario Romandini, Shayan Barootchi   +4 more
wiley   +1 more source

Towards Safety and Regulation Criteria for Clinical Applications of Decellularized Organ-Derived Matrices

Bioengineering
Whole-organ decellularization generates scaffolds containing native extracellular matrix (ECM) components with preserved tissue microarchitecture, providing a promising advancement in tissue engineering and regenerative medicine.
Elena V. A. van Hengel, Luc J. W. van der Laan, Jeroen de Jonge, Monique M. A. Verstegen   +3 more
doaj   +1 more source

Three‐Dimensional Scaffolds for Bone, Soft Tissue, and Periodontal Regeneration

Journal of Periodontal Research, EarlyView.
Three‐dimensional scaffolds offer tissue‐specific control of architecture, mechanics, porosity, and functionalisation to improve bone, soft tissue, and periodontal regeneration. ABSTRACT The oral cavity presents three distinct regenerative challenges: restoration of alveolar bone volume and stability, augmentation of soft mucogingival tissues, and ...
Reuben Staples, Jamil Alayan, Raghavendra Vamsi Anegundi, Marisca Pereira, Saraswat Basu, Sašo Ivanovski   +5 more
wiley   +1 more source

Current Strategies for Tracheal Decellularization: A Systematic Review

International Journal of Biomaterials
The process of decellularization is crucial for producing a substitute for the absent tracheal segment, and the choice of agents and methods significantly influences the outcomes.
Dhihintia Jiwangga, Ferdiansyah Mahyudin, Gondo Mastutik, null Juliana, Estya Nadya Meitavany   +4 more
doaj   +1 more source

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz, Shankara N. Varadarajan, Viktor Drel, Prakash Arullampalam, Mahmoud I. Shoulkamy, Ahmed Al‐Sabi, Brij B. Singh   +6 more
wiley   +1 more source

Application of decellularization methods for scaffold production: advantages, disadvantages, biosafety and modifications

Frontiers in Bioengineering and Biotechnology
The development of efficient, biocompatible scaffolds is an actual challenge in tissue engineering. Scaffolds derived from animal sources offer promising structural and biochemical properties but require thorough decellularization to minimize ...
O. I. Shevchuk, O. I. Shevchuk, V. V. Korcheva, N. S. Moskalenko, V. M. Kyryk, V. M. Kyryk, K. V. Kot, D. S. Krasnienkov   +7 more
doaj   +1 more source

Osteoarthritis Therapeutics: From Microenvironment Understanding to Regenerative Intervention—Current Advances and Future Perspectives

Orthopaedic Surgery, EarlyView.
This article outlines a paradigm shift in OA therapeutics, OA as a systemic disease of joint microenvironment imbalance. It synthesizes advances in targeting key pathological hubs—immune, metabolic, and senescent—and details novel regenerative strategies using engineered biomaterials and exosomes.
Yongbiao Meng, Shenghua Wu, Quanchun Liu
wiley   +1 more source