Results 101 to 110 of about 11,220 (243)
A sterilization method for human decellularized vaginal matrices
Scientific ReportsVaginal reconstruction is necessary for various congenital and acquired conditions, including vaginal aplasia, trauma, tumors, and gender incongruency. Current surgical and non-surgical treatments often result in significant complications. Decellularized
Jayson Sueters +5 more
doaj +1 more source
Advanced Science, EarlyView.Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu +10 more
wiley +1 more source
Porcine kidney xenotransplantation: From primate models to clinical reality
Animal Models and Experimental Medicine, EarlyView.In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo +3 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley +1 more source
Measurement of solution parameters on sonication decellularization treatment [PDF]
, 2014 We have developed a sonication decellularization system to decellularized biological scaffolds in short time by combining sonication and chemical method.
Y., Morimoto +4 more
core
Decellularization of ram cardiac tissue via supercritical CO2
, 2022 The decellularization method efficacy varies depending on the tissue type. There are commonly used physical, chemical and enzymatic methods. Most of the methods affect the extracellular matrix properties that will in turn alter the cell fate when the ...
Lacin, Nelisa, Cesur, Nevra Pelin
core +1 more source
Animal Models and Experimental Medicine, EarlyView.Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley +1 more source
Potential Therapeutic Applications of Novel Bioengineered Tissues and Organs Using Methods of Decellularization and Recellularization [PDF]
, 2018 The transplantation of personalized organs or tissues will benefit patients with various diseases and disorders. Decellularization is a method to generate an acellular, non-immunogenic natural scaffold.
Kuna, Vijay Kumar
core +1 more source
Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction
Advanced NanoBiomed Research, EarlyView.In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen +14 more
wiley +1 more source
Chemical treatments for decellularization in study 1.
, 2017 Chemical treatments for decellularization in study 1.
Kai Xu (122914) +7 more
core +1 more source