Results 121 to 130 of about 11,220 (243)

Application of decellularization methods for scaffold production: advantages, disadvantages, biosafety and modifications

open access: yesFrontiers in Bioengineering and Biotechnology
The development of efficient, biocompatible scaffolds is an actual challenge in tissue engineering. Scaffolds derived from animal sources offer promising structural and biochemical properties but require thorough decellularization to minimize ...
O. I. Shevchuk   +7 more
doaj   +1 more source

Fish Scales: A Multifunctional Biomaterial from Nature

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley   +1 more source

Decellularization of Porcine Lung Tissue

open access: yes, 2015
Our project aims to standardize the decellularization of a porcine lung by creating a bioreactor to house the lung, automating the decellularization process and developing a protocol that will increase the precision and the repeatability of the process ...
Reid, Lumumba   +4 more
core  

The effect of bioactive membrane in alveolar ridge preservation: A double‐blind randomized clinical trial

open access: yesJournal of Periodontology, EarlyView.
Abstract Background This randomized controlled trial aims to evaluate alveolar ridge preservation (ARP) with or without a biologically active amnion–chorion membrane (BACM). Methods Thirty patients requiring tooth extraction in the esthetic zone were randomly assigned to 2 groups.
Magdalena Orlowska   +8 more
wiley   +1 more source

Human Leucocyte Antigen: A Forgotten Criterion for Decellularization Success

open access: yes, 2023
PURPOSE: Decellularization procedures significantly progressed to reduce the risk of immune rejection in allo- or xenogenic transplantation. The validation of decellularization protocols is typically based on Crapo’s criteria, including the absence of ...
Cornu, Olivier   +9 more
core  

Endothelial Hydrogels Improve Microvascular Regeneration and Perfusion in Tracheal Scaffolds

open access: yesThe Laryngoscope, EarlyView.
Insufficient vascularization remains a major barrier to successful tracheal transplantation. This study demonstrates that an endothelial hydrogel significantly enhances graft perfusion and neovessel organization compared to non‐endothelial hydrogel controls.
Molly O. Hunter   +6 more
wiley   +1 more source

Development of a supercritical CO2 decellularization technology [PDF]

open access: yes
Decellularization of mammalian tissue describes the process by which cellular materials are removed from the extracellular matrix (ECM, Hinderer, Layland and Schenke-Layland, 2016).
Loczenski, Rabea
core  

Injectable Short Nanofiber Fragments Enable Conformal Fibrous Scaffolds for Tissue Engineering on Complex Surfaces

open access: yesMacromolecular Rapid Communications, EarlyView.
Short nanofiber fragments (SNFs) derived from electrospun PDLA/gelatin (PG) mats dynamically reassemble into conformal fibrous networks on complex substrates. This approach overcomes the geometric limitations of conventional electrospinning, enabling uniform surface coverage, enhanced wettability, and cytocompatible scaffold formation, thereby offering
Iruthayapandi Selestin Raja   +7 more
wiley   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao   +4 more
wiley   +1 more source

Identification of Autologous Tissue Sources and Optimization of a Treatment Method for Intraoperative Manufacturing of Heart Valve Constructs

open access: yesArtificial Organs, EarlyView.
The use of autologous connective tissue, such as pericardium or peritoneum, combined with controlled tissue treatment, has the potential to result in a more durable heart valve prosthesis than current commercial prostheses. ABSTRACT Introduction Valvular heart disease remains a leading cause of morbidity and mortality. Current biological and mechanical
Marvin Steitz   +17 more
wiley   +1 more source

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